GO Annotations Graph

• Symbol: Ercc5
• Name: excision repair cross-complementing rodent repair deficiency, complementation group 5
• ID: MGI:103582

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000405	bubble DNA binding	ISO	J:164563
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0003684	damaged DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0004520	DNA endonuclease activity	ISO	J:164563
Molecular Function	GO:0004520	DNA endonuclease activity	IBA	J:265628
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0004519	endonuclease activity	ISO	J:164563
Molecular Function	GO:0008047	enzyme activator activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016788	hydrolase activity, acting on ester bonds	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	IEA	J:72247
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0000993	RNA polymerase II complex binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005662	DNA replication factor A complex	ISO	J:164563
Cellular Component	GO:0000109	nucleotide-excision repair complex	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0006285	base-excision repair, AP site formation	ISO	J:164563
Biological Process	GO:0008340	determination of adult lifespan	IMP	J:89911
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IMP	J:89911
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0035264	multicellular organism growth	IMP	J:53756
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0006289	nucleotide-excision repair	ISO	J:164563
Biological Process	GO:0006289	nucleotide-excision repair	IMP	J:53756
Biological Process	GO:0050790	regulation of catalytic activity	ISO	J:164563
Biological Process	GO:0009411	response to UV	ISO	J:164563
Biological Process	GO:0009411	response to UV	IMP	J:89911
Biological Process	GO:0010225	response to UV-C	ISO	J:164563
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair	ISO	J:164563
Biological Process	GO:0009650	UV protection	IMP	J:29500
Biological Process	GO:0009650	UV protection	IDA	J:35458
Biological Process	GO:0009650	UV protection	ISO	J:73065