Xrcc5 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
MGI:104517

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051575	5'-deoxyribose-5-phosphate lyase activity	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	ISO	J:164563
Molecular Function	GO:0003684	damaged DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0045027	DNA end binding	ISO	J:164563
Molecular Function	GO:0045027	DNA end binding	ISO	J:164563
Molecular Function	GO:0003678	DNA helicase activity	IEA	J:72247
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0003690	double-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0003691	double-stranded telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:199000
Molecular Function	GO:0005515	protein binding	IPI	J:265834
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0042162	telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0042162	telomeric DNA binding	IBA	J:265628
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0034511	U3 snoRNA binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:82010
Cellular Component	GO:0070418	DNA-dependent protein kinase complex	ISO	J:164563
Cellular Component	GO:0043564	Ku70:Ku80 complex	ISO	J:164563
Cellular Component	GO:0043564	Ku70:Ku80 complex	IBA	J:265628
Cellular Component	GO:0070419	nonhomologous end joining complex	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:82010
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:164563
Cellular Component	GO:0090734	site of DNA damage	ISO	J:164563
Cellular Component	GO:0032040	small-subunit processome	ISO	J:164563
Biological Process	GO:0002218	activation of innate immune response	ISO	J:164563
Biological Process	GO:0071475	cellular hyperosmotic salinity response	ISO	J:155856
Biological Process	GO:0071480	cellular response to gamma radiation	ISO	J:164563
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0071481	cellular response to X-ray	ISO	J:155856
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006310	DNA recombination	IEA	J:60000
Biological Process	GO:0006310	DNA recombination	IEA	J:72247
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0006302	double-strand break repair	ISO	J:164563
Biological Process	GO:0006302	double-strand break repair	IMP	J:80467
Biological Process	GO:0006302	double-strand break repair	IGI	J:80467
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	NAS	J:320136
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	NAS	J:320262
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	IBA	J:265628
Biological Process	GO:0060218	hematopoietic stem cell differentiation	IMP	J:122781
Biological Process	GO:0071425	hematopoietic stem cell proliferation	IMP	J:122781
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0000237	leptotene	IMP	J:147391
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1904430	negative regulation of t-circle formation	ISO	J:164563
Biological Process	GO:0022008	neurogenesis	IMP	J:110848
Biological Process	GO:0050769	positive regulation of neurogenesis	IMP	J:110848
Biological Process	GO:0045860	positive regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:0000725	recombinational repair	NAS	J:320136
Biological Process	GO:0048660	regulation of smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0042254	ribosome biogenesis	IEA	J:60000
Biological Process	GO:0034462	small-subunit processome assembly	ISO	J:164563
Biological Process	GO:0000723	telomere maintenance	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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