GO Annotations Graph

• Symbol: Cdkn1c
• Name: cyclin dependent kinase inhibitor 1C
• ID: MGI:104564

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	IEA	J:72247
Molecular Function	GO:0140678	molecular function inhibitor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:88146
Molecular Function	GO:0004860	protein kinase inhibitor activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:104004
Cellular Component	GO:0005634	nucleus	IDA	J:104004
Cellular Component	GO:0005634	nucleus	IDA	J:104004
Cellular Component	GO:0005634	nucleus	IDA	J:152946
Biological Process	GO:0030325	adrenal gland development	IMP	J:147145
Biological Process	GO:0030325	adrenal gland development	IMP	J:147145
Biological Process	GO:0043010	camera-type eye development	IMP	J:147145
Biological Process	GO:0043010	camera-type eye development	IMP	J:147145
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0055123	digestive system development	IMP	J:147145
Biological Process	GO:0055123	digestive system development	IMP	J:147145
Biological Process	GO:0060669	embryonic placenta morphogenesis	IMP	J:147145
Biological Process	GO:0060669	embryonic placenta morphogenesis	IMP	J:147145
Biological Process	GO:0071514	genomic imprinting	IMP	J:147145
Biological Process	GO:0071514	genomic imprinting	IMP	J:147145
Biological Process	GO:0001822	kidney development	IMP	J:147145
Biological Process	GO:0001822	kidney development	IMP	J:147145
Biological Process	GO:0035264	multicellular organism growth	IMP	J:147145
Biological Process	GO:0035264	multicellular organism growth	IMP	J:147145
Biological Process	GO:0030099	myeloid cell differentiation	IGI	J:98498
Biological Process	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0033673	negative regulation of kinase activity	ISO	J:164563
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	IBA	J:265628
Biological Process	GO:0042326	negative regulation of phosphorylation	IDA	J:150904
Biological Process	GO:0042326	negative regulation of phosphorylation	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:88146
Biological Process	GO:0042551	neuron maturation	IMP	J:88146
Biological Process	GO:0001890	placenta development	IGI	J:50769
Biological Process	GO:0001890	placenta development	IMP	J:177542
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0051726	regulation of cell cycle	IEA	J:72247
Biological Process	GO:0007096	regulation of exit from mitosis	IGI	J:50769
Biological Process	GO:1902746	regulation of lens fiber cell differentiation	IGI	J:50769
Biological Process	GO:0007346	regulation of mitotic cell cycle	IEA	J:72247
Biological Process	GO:0001501	skeletal system development	IMP	J:147145
Biological Process	GO:0001501	skeletal system development	IMP	J:147145
Biological Process	GO:0060065	uterus development	IMP	J:147145
Biological Process	GO:0060065	uterus development	IMP	J:147145