GO Annotations Graph

• Symbol: Limk1
• Name: LIM domain kinase 1
• ID: MGI:104572

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:243478
Molecular Function	GO:0005515	protein binding	IPI	J:108459
Molecular Function	GO:0005515	protein binding	IPI	J:56497
Molecular Function	GO:0005515	protein binding	IPI	J:101335
Molecular Function	GO:0005515	protein binding	IPI	J:108459
Molecular Function	GO:0005515	protein binding	IPI	J:88894
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0044295	axonal growth cone	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:101335
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:108459
Cellular Component	GO:0005737	cytoplasm	IDA	J:108459
Cellular Component	GO:0005737	cytoplasm	IDA	J:108459
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	IDA	J:88894
Cellular Component	GO:0005925	focal adhesion	IDA	J:108459
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	IDA	J:243478
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:108459
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:108459
Cellular Component	GO:0016020	membrane	IDA	J:216094
Cellular Component	GO:0043005	neuron projection	IDA	J:101335
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:88894
Cellular Component	GO:0005634	nucleus	IDA	J:108459
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Biological Process	GO:0030036	actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0048675	axon extension	IGI	J:101335
Biological Process	GO:0048675	axon extension	IGI	J:101335
Biological Process	GO:0051444	negative regulation of ubiquitin-protein transferase activity	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0032233	positive regulation of actin filament bundle assembly	ISO	J:164563
Biological Process	GO:0045773	positive regulation of axon extension	IGI	J:101335
Biological Process	GO:0051496	positive regulation of stress fiber assembly	IBA	J:265628
Biological Process	GO:0051496	positive regulation of stress fiber assembly	IGI	J:91604
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0043149	stress fiber assembly	IGI	J:91604