GO Annotations Graph

• Symbol: Tnnt2
• Name: troponin T2, cardiac
• ID: MGI:104597

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0000146	microfilament motor activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:155856
Molecular Function	GO:0005200	structural constituent of cytoskeleton	IDA	J:85429
Molecular Function	GO:0005523	tropomyosin binding	ISO	J:164563
Molecular Function	GO:0005523	tropomyosin binding	IBA	J:265628
Molecular Function	GO:0030172	troponin C binding	ISO	J:164563
Molecular Function	GO:0030172	troponin C binding	IBA	J:265628
Molecular Function	GO:0031013	troponin I binding	ISO	J:155856
Molecular Function	GO:0031013	troponin I binding	ISO	J:164563
Molecular Function	GO:0031013	troponin I binding	IBA	J:265628
Cellular Component	GO:0097512	cardiac myofibril	ISO	J:164563
Cellular Component	GO:1990584	cardiac Troponin complex	ISO	J:164563
Cellular Component	GO:0030016	myofibril	ISO	J:155856
Cellular Component	GO:0030016	myofibril	IDA	J:138923
Cellular Component	GO:0030016	myofibril	IDA	J:56911
Cellular Component	GO:0030017	sarcomere	IDA	J:210551
Cellular Component	GO:0030017	sarcomere	IDA	J:84125
Cellular Component	GO:0030017	sarcomere	IDA	J:104369
Cellular Component	GO:0016528	sarcoplasm	IDA	J:98394
Cellular Component	GO:0005865	striated muscle thin filament	ISO	J:164563
Cellular Component	GO:0005861	troponin complex	ISO	J:155856
Cellular Component	GO:0005861	troponin complex	ISO	J:164563
Cellular Component	GO:0005861	troponin complex	ISO	J:164563
Cellular Component	GO:0005861	troponin complex	IBA	J:265628
Cellular Component	GO:0005861	troponin complex	IDA	J:85429
Biological Process	GO:0051764	actin crosslink formation	ISO	J:155856
Biological Process	GO:0055009	atrial cardiac muscle tissue morphogenesis	IMP	J:56911
Biological Process	GO:0055009	atrial cardiac muscle tissue morphogenesis	IMP	J:56911
Biological Process	GO:0055009	atrial cardiac muscle tissue morphogenesis	IMP	J:56911
Biological Process	GO:0060048	cardiac muscle contraction	ISO	J:164563
Biological Process	GO:0060048	cardiac muscle contraction	ISO	J:155856
Biological Process	GO:0060048	cardiac muscle contraction	IBA	J:265628
Biological Process	GO:0007507	heart development	IMP	J:48301
Biological Process	GO:0007507	heart development	IMP	J:48301
Biological Process	GO:0006936	muscle contraction	ISO	J:155856
Biological Process	GO:0006936	muscle contraction	IDA	J:85429
Biological Process	GO:0030049	muscle filament sliding	ISO	J:164563
Biological Process	GO:0032780	negative regulation of ATP-dependent activity	ISO	J:164563
Biological Process	GO:0032780	negative regulation of ATP-dependent activity	ISO	J:164563
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	ISO	J:164563
Biological Process	GO:0008016	regulation of heart contraction	ISO	J:164563
Biological Process	GO:0008016	regulation of heart contraction	IMP	J:68043
Biological Process	GO:0008016	regulation of heart contraction	IMP	J:104369
Biological Process	GO:0006937	regulation of muscle contraction	ISO	J:155856
Biological Process	GO:0032972	regulation of muscle filament sliding speed	ISO	J:155856
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0051592	response to calcium ion	ISO	J:164563
Biological Process	GO:0051592	response to calcium ion	ISO	J:164563
Biological Process	GO:0045214	sarcomere organization	IBA	J:265628
Biological Process	GO:0045214	sarcomere organization	IMP	J:56911
Biological Process	GO:0045214	sarcomere organization	IMP	J:56911
Biological Process	GO:0045214	sarcomere organization	IMP	J:56911
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	ISO	J:164563
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	IMP	J:104369