GO Annotations Graph

• Symbol: Hsd3b5
• Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
• ID: MGI:104645

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity	ISO	J:155856
Molecular Function	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0000253	3-keto sterol reductase activity	IEA	J:72245
Molecular Function	GO:0047024	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	IEA	J:72245
Molecular Function	GO:0102176	cycloeucalenone reductase activity	IEA	J:72245
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IBA	J:265628
Molecular Function	GO:0005496	steroid binding	ISO	J:155856
Molecular Function	GO:0004769	steroid delta-isomerase activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0045171	intercellular bridge	ISO	J:164563
Cellular Component	GO:0045171	intercellular bridge	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:164563
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0005758	mitochondrial intermembrane space	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Biological Process	GO:0008207	C21-steroid hormone metabolic process	IBA	J:265628
Biological Process	GO:0021766	hippocampus development	IBA	J:265628
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0042448	progesterone metabolic process	ISO	J:155856
Biological Process	GO:0050810	regulation of steroid biosynthetic process	ISO	J:155856
Biological Process	GO:0051412	response to corticosterone	IBA	J:265628
Biological Process	GO:0035634	response to stilbenoid	IEP	J:169896
Biological Process	GO:0006694	steroid biosynthetic process	ISO	J:155856
Biological Process	GO:0006694	steroid biosynthetic process	IBA	J:265628
Biological Process	GO:0008202	steroid metabolic process	IEA	J:60000