GO Annotations Graph

• Symbol: Atoh1
• Name: atonal bHLH transcription factor 1
• ID: MGI:104654

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:98522
Molecular Function	GO:0003677	DNA binding	IDA	J:87736
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:211249
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IBA	J:265628
Molecular Function	GO:0070888	E-box binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:125313
Molecular Function	GO:0005515	protein binding	IPI	J:87736
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:211249
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:112202
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:172912
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0042668	auditory receptor cell fate determination	IDA	J:104323
Biological Process	GO:0042667	auditory receptor cell fate specification	IMP	J:55694
Biological Process	GO:0061564	axon development	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IMP	J:102293
Biological Process	GO:0007420	brain development	IMP	J:79141
Biological Process	GO:0007420	brain development	IMP	J:79141
Biological Process	GO:0030154	cell differentiation	IMP	J:95110
Biological Process	GO:0021987	cerebral cortex development	IMP	J:104282
Biological Process	GO:1904019	epithelial cell apoptotic process	IMP	J:75944
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IDA	J:144981
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IDA	J:95110
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:95110
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:75944
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IDA	J:95110
Biological Process	GO:0048839	inner ear development	IMP	J:169044
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:95110
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:102293
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1904036	negative regulation of epithelial cell apoptotic process	IMP	J:75944
Biological Process	GO:0014014	negative regulation of gliogenesis	IGI	J:314376
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0097402	neuroblast migration	IMP	J:105185
Biological Process	GO:0030182	neuron differentiation	IMP	J:90130
Biological Process	GO:0048663	neuron fate commitment	IBA	J:265628
Biological Process	GO:0001764	neuron migration	IMP	J:105185
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:218237
Biological Process	GO:0045609	positive regulation of inner ear auditory receptor cell differentiation	IDA	J:64679
Biological Process	GO:0045609	positive regulation of inner ear auditory receptor cell differentiation	IDA	J:144981
Biological Process	GO:2000982	positive regulation of inner ear receptor cell differentiation	IMP	J:108846
Biological Process	GO:2000982	positive regulation of inner ear receptor cell differentiation	IMP	J:169044
Biological Process	GO:0045666	positive regulation of neuron differentiation	IDA	J:172912
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:211249
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:98522
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:104282
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:112202
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0045664	regulation of neuron differentiation	IDA	J:87736
Biological Process	GO:0007423	sensory organ development	IBA	J:265628
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:98522