GO Annotations Graph

• Symbol: Rora
• Name: RAR-related orphan receptor alpha
• ID: MGI:104661

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	IPI	J:87181
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:23754
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:199687
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:20436
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:73065
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:131020
Molecular Function	GO:0098531	ligand-activated transcription factor activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0008142	oxysterol binding	ISO	J:164563
Molecular Function	GO:0008142	oxysterol binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:116123
Molecular Function	GO:0005515	protein binding	IPI	J:213898
Molecular Function	GO:0005515	protein binding	IPI	J:200375
Molecular Function	GO:0005515	protein binding	IPI	J:213087
Molecular Function	GO:0005515	protein binding	IPI	J:148702
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:92557
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:92557
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:155827
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISS	J:124837
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:206917
Molecular Function	GO:0001223	transcription coactivator binding	IPI	J:142097
Molecular Function	GO:0001223	transcription coactivator binding	IPI	J:122764
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:164563
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Molecular Function	GO:0001222	transcription corepressor binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-1368101
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663256
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663266
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663291
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663294
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5669318
Cellular Component	GO:0005634	nucleus	IDA	J:199687
Cellular Component	GO:0005634	nucleus	IDA	J:213087
Cellular Component	GO:0005634	nucleus	IDA	J:206917
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:155827
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0071347	cellular response to interleukin-1	IDA	J:155827
Biological Process	GO:0036315	cellular response to sterol	ISO	J:164563
Biological Process	GO:0071356	cellular response to tumor necrosis factor	IDA	J:155827
Biological Process	GO:0021930	cerebellar granule cell precursor proliferation	IMP	J:87181
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IMP	J:39065
Biological Process	GO:0046068	cGMP metabolic process	IMP	J:18352
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:206917
Biological Process	GO:0032922	circadian regulation of gene expression	IDA	J:199687
Biological Process	GO:0030522	intracellular receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0042692	muscle cell differentiation	ISO	J:164563
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IMP	J:148702
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	IBA	J:265628
Biological Process	GO:0006809	nitric oxide biosynthetic process	IMP	J:18352
Biological Process	GO:0042753	positive regulation of circadian rhythm	IDA	J:199687
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:213898
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:213087
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:92557
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155827
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:92557
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:92557
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	ISO	J:164563
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:209475
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:206917
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:20436
Biological Process	GO:0010906	regulation of glucose metabolic process	IMP	J:205671
Biological Process	GO:0043030	regulation of macrophage activation	IMP	J:2228
Biological Process	GO:0008589	regulation of smoothened signaling pathway	IMP	J:87181
Biological Process	GO:0019218	regulation of steroid metabolic process	IMP	J:207076
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:131020
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:148702
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0072539	T-helper 17 cell differentiation	IMP	J:131020
Biological Process	GO:0070328	triglyceride homeostasis	IMP	J:124837
Biological Process	GO:0070328	triglyceride homeostasis	IMP	J:206917
Biological Process	GO:0070328	triglyceride homeostasis	ISO	J:164563
Biological Process	GO:0006805	xenobiotic metabolic process	IMP	J:207076