GO Annotations Graph

• Symbol: Tfap2b
• Name: transcription factor AP-2 beta
• ID: MGI:104672

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:175832
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:28698
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:175832
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:86250
Molecular Function	GO:0005515	protein binding	IPI	J:76593
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:175832
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:314366
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0048856	anatomical structure development	IBA	J:265628
Biological Process	GO:0035909	aorta morphogenesis	IMP	J:175832
Biological Process	GO:0072044	collecting duct development	IMP	J:83000
Biological Process	GO:0072017	distal tubule development	IMP	J:83000
Biological Process	GO:0097070	ductus arteriosus closure	IMP	J:175832
Biological Process	GO:0097070	ductus arteriosus closure	IMP	J:152650
Biological Process	GO:0045444	fat cell differentiation	IEP	J:177161
Biological Process	GO:0035136	forelimb morphogenesis	IMP	J:175832
Biological Process	GO:0010467	gene expression	IMP	J:152650
Biological Process	GO:0006006	glucose metabolic process	ISO	J:164563
Biological Process	GO:0035137	hindlimb morphogenesis	IMP	J:175832
Biological Process	GO:0001822	kidney development	IMP	J:42260
Biological Process	GO:0072210	metanephric nephron development	IEP	J:28698
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:177155
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:173638
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:173638
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:177155
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:175832
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:28698
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:76593
Biological Process	GO:0030510	regulation of BMP signaling pathway	IMP	J:175832
Biological Process	GO:0045595	regulation of cell differentiation	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0050796	regulation of insulin secretion	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:175832
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0007423	sensory organ development	IEP	J:28698
Biological Process	GO:0043588	skin development	IEP	J:28698
Biological Process	GO:0048745	smooth muscle tissue development	IMP	J:152650
Biological Process	GO:0048485	sympathetic nervous system development	IGI	J:173638
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:28698
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:28698
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:76593