GO Annotations Graph

• Symbol: Col4a3
• Name: collagen, type IV, alpha 3
• ID: MGI:104688

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	IBA	J:265628
Molecular Function	GO:0030020	extracellular matrix structural constituent conferring tensile strength	RCA	J:265607
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Cellular Component	GO:0005604	basement membrane	ISO	J:164563
Cellular Component	GO:0005604	basement membrane	IDA	J:132545
Cellular Component	GO:0005604	basement membrane	IBA	J:265628
Cellular Component	GO:0005604	basement membrane	IDA	J:139122
Cellular Component	GO:0005604	basement membrane	IDA	J:74207
Cellular Component	GO:0005581	collagen trimer	IEA	J:60000
Cellular Component	GO:0005581	collagen trimer	IEA	J:72247
Cellular Component	GO:0005587	collagen type IV trimer	ISO	J:164563
Cellular Component	GO:0005587	collagen type IV trimer	IDA	J:78275
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007166	cell surface receptor signaling pathway	IDA	J:120382
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	IGI	J:64375
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	IGI	J:64375
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	IGI	J:64375
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	IGI	J:64375
Biological Process	GO:0072577	endothelial cell apoptotic process	ISO	J:164563
Biological Process	GO:0030198	extracellular matrix organization	IBA	J:265628
Biological Process	GO:0032836	glomerular basement membrane development	IMP	J:103978
Biological Process	GO:0016525	negative regulation of angiogenesis	IDA	J:120399
Biological Process	GO:0016525	negative regulation of angiogenesis	ISO	J:164563
Biological Process	GO:1905563	negative regulation of vascular endothelial cell proliferation	ISO	J:164563