GO Annotations Graph

• Symbol: Meis1
• Name: Meis homeobox 1
• ID: MGI:104717

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:147470
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:43726
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:211245
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:55892
Molecular Function	GO:0005515	protein binding	IPI	J:42999
Molecular Function	GO:0005515	protein binding	IPI	J:45106
Molecular Function	GO:0005515	protein binding	IPI	J:43726
Molecular Function	GO:0005515	protein binding	IPI	J:43726
Molecular Function	GO:0005515	protein binding	IPI	J:55892
Molecular Function	GO:0005515	protein binding	IPI	J:43726
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:211245
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:45106
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:78468
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:93149
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:117676
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:42999
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:119671
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:95309
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621004
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5693628
Cellular Component	GO:0005634	nucleus	IDA	J:95882
Cellular Component	GO:0005634	nucleus	IDA	J:119671
Cellular Component	GO:0005634	nucleus	IDA	J:118901
Cellular Component	GO:0005634	nucleus	IDA	J:42999
Cellular Component	GO:0005634	nucleus	IDA	J:166594
Cellular Component	GO:0005634	nucleus	IDA	J:95882
Cellular Component	GO:0005634	nucleus	IDA	J:63180
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:45106
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:43726
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:78468
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:55892
Biological Process	GO:0001525	angiogenesis	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IMP	J:87890
Biological Process	GO:0009887	animal organ morphogenesis	IBA	J:265628
Biological Process	GO:0048514	blood vessel morphogenesis	IMP	J:98307
Biological Process	GO:0007420	brain development	IBA	J:265628
Biological Process	GO:0061049	cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:0060216	definitive hemopoiesis	IMP	J:98307
Biological Process	GO:0009880	embryonic pattern specification	IBA	J:265628
Biological Process	GO:0001654	eye development	IBA	J:265628
Biological Process	GO:0030097	hemopoiesis	IBA	J:265628
Biological Process	GO:0030097	hemopoiesis	IMP	J:87890
Biological Process	GO:0002089	lens morphogenesis in camera-type eye	IMP	J:87890
Biological Process	GO:0007626	locomotory behavior	IMP	J:215363
Biological Process	GO:0035855	megakaryocyte development	IMP	J:171033
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	IDA	J:190003
Biological Process	GO:0045665	negative regulation of neuron differentiation	IGI	J:131060
Biological Process	GO:0045665	negative regulation of neuron differentiation	IGI	J:131060
Biological Process	GO:0008284	positive regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:211245
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:78468
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IC	J:55892