GO Annotations Graph

• Symbol: Kcnj2
• Name: potassium inwardly-rectifying channel, subfamily J, member 2
• ID: MGI:104744

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	IPI	J:177217
Molecular Function	GO:0042802	identical protein binding	IPI	J:210915
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005242	inward rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0005242	inward rectifier potassium channel activity	TAS	Reactome:R-MMU-9729881
Molecular Function	GO:0005242	inward rectifier potassium channel activity	IBA	J:265628
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:113938
Molecular Function	GO:0005515	protein binding	IPI	J:114059
Molecular Function	GO:0005515	protein binding	IPI	J:177217
Molecular Function	GO:0005515	protein binding	IPI	J:114113
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9729881
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005790	smooth endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Biological Process	GO:0086001	cardiac muscle cell action potential	IMP	J:94675
Biological Process	GO:0086002	cardiac muscle cell action potential involved in contraction	ISO	J:164563
Biological Process	GO:0015693	magnesium ion transport	IDA	J:18355
Biological Process	GO:0086011	membrane repolarization during action potential	ISO	J:164563
Biological Process	GO:0086013	membrane repolarization during cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:1990573	potassium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:1990573	potassium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006813	potassium ion transport	ISO	J:164563
Biological Process	GO:0051289	protein homotetramerization	ISO	J:164563
Biological Process	GO:0086004	regulation of cardiac muscle cell contraction	ISO	J:155856
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	ISO	J:164563
Biological Process	GO:0060306	regulation of membrane repolarization	ISO	J:164563
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IBA	J:265628
Biological Process	GO:0014861	regulation of skeletal muscle contraction via regulation of action potential	ISO	J:164563
Biological Process	GO:0055119	relaxation of cardiac muscle	ISO	J:164563
Biological Process	GO:0090076	relaxation of skeletal muscle	ISO	J:164563