GO Annotations Graph

• Symbol: Nfasc
• Name: neurofascin
• ID: MGI:104753

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0098632	cell-cell adhesion mediator activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:203534
Molecular Function	GO:0086080	protein binding involved in heterotypic cell-cell adhesion	IGI	J:166099
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0030424	axon	IDA	J:122943
Cellular Component	GO:0030424	axon	IDA	J:93895
Cellular Component	GO:0043194	axon initial segment	ISO	J:155856
Cellular Component	GO:0043194	axon initial segment	IDA	J:228724
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0033268	node of Ranvier	IDA	J:145846
Cellular Component	GO:0033268	node of Ranvier	IDA	J:219896
Cellular Component	GO:0033268	node of Ranvier	ISO	J:155856
Cellular Component	GO:0033268	node of Ranvier	ISO	J:155856
Cellular Component	GO:0033010	paranodal junction	IDA	J:145846
Cellular Component	GO:0033010	paranodal junction	IDA	J:127609
Cellular Component	GO:0033270	paranode region of axon	IDA	J:85500
Cellular Component	GO:0033270	paranode region of axon	IDA	J:109037
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-373731
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:93895
Cellular Component	GO:0097454	Schwann cell microvillus	ISO	J:155856
Cellular Component	GO:0005918	septate junction	IDA	J:235660
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IDA	J:93895
Biological Process	GO:0007420	brain development	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0045162	clustering of voltage-gated sodium channels	IMP	J:166099
Biological Process	GO:0042552	myelination	IEA	J:72247
Biological Process	GO:0030913	paranodal junction assembly	IMP	J:145846
Biological Process	GO:0030913	paranodal junction assembly	IMP	J:107591
Biological Process	GO:0030913	paranodal junction assembly	IMP	J:159621
Biological Process	GO:0007422	peripheral nervous system development	IEA	J:72247
Biological Process	GO:0071205	protein localization to juxtaparanode region of axon	IMP	J:159621
Biological Process	GO:0002175	protein localization to paranode region of axon	IMP	J:159621
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:0050808	synapse organization	IMP	J:93895
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:107591