GO Annotations Graph

• Symbol: Adra1b
• Name: adrenergic receptor, alpha 1b
• ID: MGI:104774

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004935	adrenergic receptor activity	IEA	J:72247
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	ISO	J:155856
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	IBA	J:265628
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	IMP	J:83876
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	IMP	J:43591
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	IDA	J:76004
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	IDA	J:18949
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	IMP	J:43591
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	IMP	J:43591
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	IGI	J:83876
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	IDA	J:76004
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0014704	intercalated disc	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:76004
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Biological Process	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007512	adult heart development	IGI	J:83876
Biological Process	GO:0048148	behavioral response to cocaine	IMP	J:76004
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:95771
Biological Process	GO:0061049	cell growth involved in cardiac muscle cell development	IGI	J:83876
Biological Process	GO:0007267	cell-cell signaling	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0042593	glucose homeostasis	IMP	J:87718
Biological Process	GO:0005980	glycogen catabolic process	IMP	J:87718
Biological Process	GO:0005980	glycogen catabolic process	IMP	J:87718
Biological Process	GO:0007626	locomotory behavior	IMP	J:68177
Biological Process	GO:0045818	negative regulation of glycogen catabolic process	IMP	J:87718
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	ISO	J:136004
Biological Process	GO:0150099	neuron-glial cell signaling	IGI	J:273582
Biological Process	GO:0035265	organ growth	IGI	J:83876
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	IBA	J:265628
Biological Process	GO:0045819	positive regulation of glycogen catabolic process	IMP	J:87718
Biological Process	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine	IBA	J:265628
Biological Process	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine	IGI	J:83876
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	IBA	J:265628
Biological Process	GO:0001997	positive regulation of the force of heart contraction by epinephrine-norepinephrine	IGI	J:83036
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:255410
Biological Process	GO:0055117	regulation of cardiac muscle contraction	IEA	J:72247
Biological Process	GO:0006937	regulation of muscle contraction	IEA	J:72247
Biological Process	GO:0019229	regulation of vasoconstriction	IEA	J:72247
Biological Process	GO:0001975	response to amphetamine	IMP	J:76004
Biological Process	GO:0001975	response to amphetamine	IMP	J:84429
Biological Process	GO:0009725	response to hormone	ISO	J:155856
Biological Process	GO:0043278	response to morphine	IMP	J:76004
Biological Process	GO:0048545	response to steroid hormone	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0001987	vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure	IMP	J:43591
Biological Process	GO:0008542	visual learning	IMP	J:68177