Symbol Name ID |
Prkdc
protein kinase, DNA activated, catalytic polypeptide MGI:104779 |
Category | GO ID | Classification Term | Evidence | Reference | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Molecular Function | GO:0005524 | ATP binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0004677 | DNA-dependent protein kinase activity | ISO | J:73065 | |||||||||
Molecular Function | GO:0004677 | DNA-dependent protein kinase activity | IDA | J:204750 | |||||||||
Molecular Function | GO:0003690 | double-stranded DNA binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0003690 | double-stranded DNA binding | IDA | J:173439 | |||||||||
Molecular Function | GO:0019899 | enzyme binding | IPI | J:168151 | |||||||||
Molecular Function | GO:0016301 | kinase activity | IEA | J:72247 | |||||||||
Molecular Function | GO:0016301 | kinase activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0140678 | molecular function inhibitor activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0000166 | nucleotide binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:207239 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:212794 | |||||||||
Molecular Function | GO:0019904 | protein domain specific binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0004672 | protein kinase activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | IBA | J:265628 | |||||||||
Molecular Function | GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0016740 | transferase activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0034511 | U3 snoRNA binding | ISO | J:164563 | |||||||||
Cellular Component | GO:0000785 | chromatin | ISO | J:164563 | |||||||||
Cellular Component | GO:0070418 | DNA-dependent protein kinase complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex | ISO | J:73065 | |||||||||
Cellular Component | GO:0070419 | nonhomologous end joining complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0005730 | nucleolus | ISO | J:164563 | |||||||||
Cellular Component | GO:0005654 | nucleoplasm | ISO | J:164563 | |||||||||
Cellular Component | GO:0005634 | nucleus | ISO | J:164563 | |||||||||
Cellular Component | GO:0005634 | nucleus | IBA | J:265628 | |||||||||
Cellular Component | GO:0005634 | nucleus | IDA | J:82010 | |||||||||
Cellular Component | GO:0032991 | protein-containing complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0032993 | protein-DNA complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0032040 | small-subunit processome | ISO | J:164563 | |||||||||
Cellular Component | GO:0005667 | transcription regulator complex | ISO | J:164563 | |||||||||
Biological Process | GO:0002218 | activation of innate immune response | ISO | J:164563 | |||||||||
Biological Process | GO:0002326 | B cell lineage commitment | IMP | J:31364 | |||||||||
Biological Process | GO:0002326 | B cell lineage commitment | IMP | J:31364 | |||||||||
Biological Process | GO:0002326 | B cell lineage commitment | IMP | J:31364 | |||||||||
Biological Process | GO:0007420 | brain development | IGI | J:108789 | |||||||||
Biological Process | GO:0032869 | cellular response to insulin stimulus | ISO | J:164563 | |||||||||
Biological Process | GO:0006974 | DNA damage response | ISO | J:164563 | |||||||||
Biological Process | GO:0006281 | DNA repair | IEA | J:60000 | |||||||||
Biological Process | GO:0006281 | DNA repair | IEA | J:72247 | |||||||||
Biological Process | GO:0006302 | double-strand break repair | ISO | J:164563 | |||||||||
Biological Process | GO:0006302 | double-strand break repair | IBA | J:265628 | |||||||||
Biological Process | GO:0006302 | double-strand break repair | IMP | J:73443 | |||||||||
Biological Process | GO:0006302 | double-strand break repair | IMP | J:82010 | |||||||||
Biological Process | GO:0006303 | double-strand break repair via nonhomologous end joining | NAS | J:320262 | |||||||||
Biological Process | GO:0006303 | double-strand break repair via nonhomologous end joining | IMP | J:204750 | |||||||||
Biological Process | GO:0035234 | ectopic germ cell programmed cell death | IMP | J:118902 | |||||||||
Biological Process | GO:0007507 | heart development | IGI | J:108789 | |||||||||
Biological Process | GO:0002327 | immature B cell differentiation | IMP | J:50222 | |||||||||
Biological Process | GO:0002376 | immune system process | IEA | J:60000 | |||||||||
Biological Process | GO:0033152 | immunoglobulin V(D)J recombination | IBA | J:265628 | |||||||||
Biological Process | GO:0033152 | immunoglobulin V(D)J recombination | IMP | J:50222 | |||||||||
Biological Process | GO:0045087 | innate immune response | IEA | J:60000 | |||||||||
Biological Process | GO:0008630 | intrinsic apoptotic signaling pathway in response to DNA damage | IBA | J:265628 | |||||||||
Biological Process | GO:0008630 | intrinsic apoptotic signaling pathway in response to DNA damage | IMP | J:82010 | |||||||||
Biological Process | GO:0030098 | lymphocyte differentiation | IMP | J:17426 | |||||||||
Biological Process | GO:0000460 | maturation of 5.8S rRNA | ISO | J:164563 | |||||||||
Biological Process | GO:0031571 | mitotic G1 DNA damage checkpoint signaling | ISO | J:164563 | |||||||||
Biological Process | GO:0043066 | negative regulation of apoptotic process | ISO | J:164563 | |||||||||
Biological Process | GO:2000773 | negative regulation of cellular senescence | ISO | J:155856 | |||||||||
Biological Process | GO:0002638 | negative regulation of immunoglobulin production | ISO | J:155856 | |||||||||
Biological Process | GO:0045824 | negative regulation of innate immune response | ISO | J:164563 | |||||||||
Biological Process | GO:0001933 | negative regulation of protein phosphorylation | IMP | J:207239 | |||||||||
Biological Process | GO:2001229 | negative regulation of response to gamma radiation | ISO | J:155856 | |||||||||
Biological Process | GO:0018105 | peptidyl-serine phosphorylation | ISO | J:73065 | |||||||||
Biological Process | GO:0018107 | peptidyl-threonine phosphorylation | ISO | J:164563 | |||||||||
Biological Process | GO:0016310 | phosphorylation | IEA | J:60000 | |||||||||
Biological Process | GO:0043065 | positive regulation of apoptotic process | IMP | J:118902 | |||||||||
Biological Process | GO:0048639 | positive regulation of developmental growth | ISO | J:155856 | |||||||||
Biological Process | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining | ISO | J:164563 | |||||||||
Biological Process | GO:0045648 | positive regulation of erythrocyte differentiation | IMP | J:287062 | |||||||||
Biological Process | GO:0048146 | positive regulation of fibroblast proliferation | ISO | J:155856 | |||||||||
Biological Process | GO:0002684 | positive regulation of immune system process | ISO | J:155856 | |||||||||
Biological Process | GO:0045621 | positive regulation of lymphocyte differentiation | IMP | J:287062 | |||||||||
Biological Process | GO:1905221 | positive regulation of platelet formation | IMP | J:287062 | |||||||||
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | ISO | J:164563 | |||||||||
Biological Process | GO:0045727 | positive regulation of translation | IMP | J:287062 | |||||||||
Biological Process | GO:0002328 | pro-B cell differentiation | IMP | J:50222 | |||||||||
Biological Process | GO:0031648 | protein destabilization | IDA | J:92391 | |||||||||
Biological Process | GO:0006468 | protein phosphorylation | ISO | J:164563 | |||||||||
Biological Process | GO:0006468 | protein phosphorylation | IBA | J:265628 | |||||||||
Biological Process | GO:0042752 | regulation of circadian rhythm | IMP | J:207239 | |||||||||
Biological Process | GO:0050678 | regulation of epithelial cell proliferation | ISO | J:164563 | |||||||||
Biological Process | GO:1902036 | regulation of hematopoietic stem cell differentiation | IMP | J:287062 | |||||||||
Biological Process | GO:0048660 | regulation of smooth muscle cell proliferation | ISO | J:164563 | |||||||||
Biological Process | GO:0010332 | response to gamma radiation | IMP | J:50222 | |||||||||
Biological Process | GO:0010212 | response to ionizing radiation | IMP | J:173439 | |||||||||
Biological Process | GO:0048511 | rhythmic process | IEA | J:60000 | |||||||||
Biological Process | GO:0042254 | ribosome biogenesis | IEA | J:60000 | |||||||||
Biological Process | GO:0034462 | small-subunit processome assembly | ISO | J:164563 | |||||||||
Biological Process | GO:0001756 | somitogenesis | IGI | J:108789 | |||||||||
Biological Process | GO:0048536 | spleen development | ISO | J:155856 | |||||||||
Biological Process | GO:0033077 | T cell differentiation in thymus | IMP | J:50222 | |||||||||
Biological Process | GO:0002360 | T cell lineage commitment | IMP | J:31364 | |||||||||
Biological Process | GO:0002360 | T cell lineage commitment | IMP | J:31364 | |||||||||
Biological Process | GO:0002360 | T cell lineage commitment | IMP | J:31364 | |||||||||
Biological Process | GO:0033153 | T cell receptor V(D)J recombination | IMP | J:50222 | |||||||||
Biological Process | GO:0016233 | telomere capping | ISO | J:164563 | |||||||||
Biological Process | GO:0000723 | telomere maintenance | IBA | J:265628 | |||||||||
Biological Process | GO:0000723 | telomere maintenance | IMP | J:88560 | |||||||||
Biological Process | GO:0048538 | thymus development | ISO | J:155856 | |||||||||
Biological Process | GO:0033151 | V(D)J recombination | IGI | J:204750 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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