GO Annotations Graph

• Symbol: Pls1
• Name: plastin 1 (I-isoform)
• ID: MGI:104809

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:216723
Cellular Component	GO:0005884	actin filament	IBA	J:265628
Cellular Component	GO:0032432	actin filament bundle	IBA	J:265628
Cellular Component	GO:0005903	brush border	IDA	J:219622
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:26070
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032420	stereocilium	IDA	J:216416
Cellular Component	GO:1990357	terminal web	IDA	J:216723
Biological Process	GO:0051017	actin filament bundle assembly	IBA	J:265628
Biological Process	GO:0051639	actin filament network formation	IBA	J:265628
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	IMP	J:216416
Biological Process	GO:0001951	intestinal D-glucose absorption	IGI	J:219622
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IGI	J:219622
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	IMP	J:219622
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	IGI	J:219622
Biological Process	GO:0032532	regulation of microvillus length	IGI	J:219622
Biological Process	GO:1902896	terminal web assembly	IGI	J:219622
Biological Process	GO:1902896	terminal web assembly	IMP	J:216723
Biological Process	GO:0060121	vestibular receptor cell stereocilium organization	IMP	J:216416