GO Annotations Graph

• Symbol: Plaa
• Name: phospholipase A2, activating protein
• ID: MGI:104810

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016005	phospholipase A2 activator activity	IDA	J:28587
Molecular Function	GO:0005515	protein binding	IPI	J:153239
Molecular Function	GO:0005515	protein binding	IPI	J:72860
Molecular Function	GO:0043130	ubiquitin binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:240526
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:240526
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0045202	synapse	IDA	J:240526
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0006954	inflammatory response	IDA	J:28587
Biological Process	GO:0016236	macroautophagy	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	IMP	J:240526
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:1903861	positive regulation of dendrite extension	IMP	J:240526
Biological Process	GO:2001224	positive regulation of neuron migration	IMP	J:240526
Biological Process	GO:0032430	positive regulation of phospholipase A2 activity	ISO	J:164563
Biological Process	GO:1903423	positive regulation of synaptic vesicle recycling	IMP	J:240526
Biological Process	GO:0006693	prostaglandin metabolic process	IMP	J:250427
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0010992	ubiquitin recycling	IBA	J:265628
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IMP	J:240526