GO Annotations Graph

• Symbol: Fxr1
• Name: FMR1 autosomal homolog 1
• ID: MGI:104860

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140693	molecular condensate scaffold activity	IDA	J:291328
Molecular Function	GO:0140693	molecular condensate scaffold activity	IDA	J:332641
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	ISO	J:164563
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	IDA	J:218753
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	IDA	J:96927
Molecular Function	GO:0003730	mRNA 3'-UTR binding	ISO	J:164563
Molecular Function	GO:0003730	mRNA 3'-UTR binding	IBA	J:265628
Molecular Function	GO:0003729	mRNA binding	IDA	J:291328
Molecular Function	GO:0003729	mRNA binding	IDA	J:242048
Molecular Function	GO:0003729	mRNA binding	IDA	J:332641
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:88664
Molecular Function	GO:0005515	protein binding	IPI	J:231210
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	IBA	J:265628
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0033592	RNA strand annealing activity	ISO	J:164563
Molecular Function	GO:0045182	translation regulator activity	ISO	J:164563
Molecular Function	GO:0045182	translation regulator activity	IBA	J:265628
Molecular Function	GO:0045182	translation regulator activity	IDA	J:332641
Molecular Function	GO:0045182	translation regulator activity	IDA	J:332641
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0030424	axon	IDA	J:179583
Cellular Component	GO:0043034	costamere	IDA	J:91191
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:332641
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	IBA	J:265628
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:276784
Cellular Component	GO:0030425	dendrite	IDA	J:179583
Cellular Component	GO:1902737	dendritic filopodium	IBA	J:265628
Cellular Component	GO:0043197	dendritic spine	IBA	J:265628
Cellular Component	GO:0043197	dendritic spine	IDA	J:179583
Cellular Component	GO:0044326	dendritic spine neck	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263455
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263455
Cellular Component	GO:0030426	growth cone	IBA	J:265628
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	IDA	J:332641
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:125970
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:179583
Cellular Component	GO:0005844	polysome	IBA	J:265628
Cellular Component	GO:0005844	polysome	IDA	J:179583
Cellular Component	GO:0098794	postsynapse	IDA	J:263455
Cellular Component	GO:0098794	postsynapse	IDA	J:263455
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0098793	presynapse	IBA	J:265628
Cellular Component	GO:0035770	ribonucleoprotein granule	IDA	J:179583
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0021542	dentate gyrus development	IMP	J:242048
Biological Process	GO:0061157	mRNA destabilization	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007517	muscle organ development	IDA	J:291328
Biological Process	GO:0007517	muscle organ development	IMP	J:276784
Biological Process	GO:0007517	muscle organ development	ISO	J:164563
Biological Process	GO:0007517	muscle organ development	IMP	J:91191
Biological Process	GO:0050728	negative regulation of inflammatory response	ISO	J:164563
Biological Process	GO:1900272	negative regulation of long-term synaptic potentiation	IMP	J:218753
Biological Process	GO:0017148	negative regulation of translation	IDA	J:218753
Biological Process	GO:0017148	negative regulation of translation	IBA	J:265628
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IDA	J:96927
Biological Process	GO:0140694	non-membrane-bounded organelle assembly	IDA	J:332641
Biological Process	GO:0051292	nuclear pore complex assembly	ISO	J:164563
Biological Process	GO:0051664	nuclear pore localization	ISO	J:164563
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IBA	J:265628
Biological Process	GO:0045727	positive regulation of translation	ISO	J:164563
Biological Process	GO:0045727	positive regulation of translation	IBA	J:265628
Biological Process	GO:0045727	positive regulation of translation	IDA	J:332641
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	IMP	J:305336
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	IDA	J:96927
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IBA	J:265628
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	IMP	J:305336
Biological Process	GO:0051489	regulation of filopodium assembly	IBA	J:265628
Biological Process	GO:0043488	regulation of mRNA stability	IBA	J:265628
Biological Process	GO:0050767	regulation of neurogenesis	IDA	J:242048
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	IMP	J:218753
Biological Process	GO:0006417	regulation of translation	IEA	J:72247
Biological Process	GO:0060538	skeletal muscle organ development	ISO	J:164563
Biological Process	GO:0060538	skeletal muscle organ development	IDA	J:276784
Biological Process	GO:0007286	spermatid development	IDA	J:332641