GO Annotations Graph

• Symbol: Rest
• Name: RE1-silencing transcription factor
• ID: MGI:104897

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:109077
Molecular Function	GO:0003682	chromatin binding	IDA	J:188795
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IDA	J:91474
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA	J:72247
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:172987
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:273586
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:321396
Molecular Function	GO:0005515	protein binding	IPI	J:172884
Molecular Function	GO:0005515	protein binding	IPI	J:273587
Molecular Function	GO:0005515	protein binding	IPI	J:172884
Molecular Function	GO:0005515	protein binding	IPI	J:143774
Molecular Function	GO:0005515	protein binding	IPI	J:235128
Molecular Function	GO:0005515	protein binding	IPI	J:61357
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	IDA	J:256101
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:155856
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:172987
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:273586
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:273587
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:98945
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IBA	J:265628
Cellular Component	GO:0000785	chromatin	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:173137
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:273587
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:98945
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:173137
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:172884
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0017053	transcription repressor complex	IDA	J:172987
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:164563
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:155856
Cellular Component	GO:0017053	transcription repressor complex	IBA	J:265628
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	IMP	J:265659
Biological Process	GO:0060379	cardiac muscle cell myoblast differentiation	IDA	J:173137
Biological Process	GO:0071257	cellular response to electrical stimulus	ISO	J:164563
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	ISO	J:164563
Biological Process	GO:0033554	cellular response to stress	IDA	J:256101
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	IMP	J:265659
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	IMP	J:202604
Biological Process	GO:0099563	modification of synaptic structure	ISO	J:155856
Biological Process	GO:0043922	negative regulation by host of viral transcription	ISO	J:164563
Biological Process	GO:0032348	negative regulation of aldosterone biosynthetic process	ISO	J:164563
Biological Process	GO:0032348	negative regulation of aldosterone biosynthetic process	ISO	J:155856
Biological Process	GO:2000798	negative regulation of amniotic stem cell differentiation	ISO	J:164563
Biological Process	GO:0045955	negative regulation of calcium ion-dependent exocytosis	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:2000065	negative regulation of cortisol biosynthetic process	ISO	J:164563
Biological Process	GO:2000065	negative regulation of cortisol biosynthetic process	ISO	J:155856
Biological Process	GO:2000706	negative regulation of dense core granule biogenesis	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:172987
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:265602
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:91474
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:98945
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:50169
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:273586
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0046676	negative regulation of insulin secretion	ISO	J:164563
Biological Process	GO:2000740	negative regulation of mesenchymal stem cell differentiation	ISO	J:164563
Biological Process	GO:1902894	negative regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0050768	negative regulation of neurogenesis	IGI	J:120378
Biological Process	GO:0045665	negative regulation of neuron differentiation	IDA	J:98945
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:242726
Biological Process	GO:0045665	negative regulation of neuron differentiation	ISO	J:164563
Biological Process	GO:0045665	negative regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:0045665	negative regulation of neuron differentiation	IBA	J:265628
Biological Process	GO:1903204	negative regulation of oxidative stress-induced neuron death	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:2000678	negative regulation of transcription regulatory region DNA binding	IDA	J:273587
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:265659
Biological Process	GO:0097150	neuronal stem cell population maintenance	IMP	J:242726
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:265659
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:273587
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:273586
Biological Process	GO:0045666	positive regulation of neuron differentiation	IMP	J:265602
Biological Process	GO:1903223	positive regulation of oxidative stress-induced neuron death	ISO	J:155856
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	ISO	J:164563
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IMP	J:265602
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	IDA	J:256101
Biological Process	GO:0045667	regulation of osteoblast differentiation	IMP	J:221584
Biological Process	GO:1903203	regulation of oxidative stress-induced neuron death	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IEA	J:72247
Biological Process	GO:0001666	response to hypoxia	ISO	J:164563
Biological Process	GO:0002931	response to ischemia	ISO	J:155856
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:242726