GO Annotations Graph

• Symbol: Tead2
• Name: TEA domain family member 2
• ID: MGI:104904

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097718	disordered domain specific binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:27765
Molecular Function	GO:0003677	DNA binding	IDA	J:46262
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:182976
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:87726
Molecular Function	GO:0005515	protein binding	IPI	J:65012
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:102951
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9796226
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0140552	TEAD-YAP complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:102951
Biological Process	GO:0071300	cellular response to retinoic acid	IDA	J:182976
Biological Process	GO:0003143	embryonic heart tube morphogenesis	IGI	J:131426
Biological Process	GO:0003143	embryonic heart tube morphogenesis	IGI	J:131426
Biological Process	GO:0048568	embryonic organ development	IBA	J:265628
Biological Process	GO:0035329	hippo signaling	ISO	J:164563
Biological Process	GO:0035329	hippo signaling	IBA	J:265628
Biological Process	GO:0048368	lateral mesoderm development	IGI	J:131426
Biological Process	GO:0048368	lateral mesoderm development	IGI	J:131426
Biological Process	GO:0060548	negative regulation of cell death	IGI	J:175338
Biological Process	GO:0001843	neural tube closure	IMP	J:127233
Biological Process	GO:0030903	notochord development	IGI	J:131426
Biological Process	GO:0030903	notochord development	IGI	J:131426
Biological Process	GO:0048339	paraxial mesoderm development	IGI	J:131426
Biological Process	GO:0048339	paraxial mesoderm development	IGI	J:131426
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:46262
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:87726
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:182976
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:102951
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:2000736	regulation of stem cell differentiation	IMP	J:182976
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:87726
Biological Process	GO:0001570	vasculogenesis	IGI	J:131426
Biological Process	GO:0001570	vasculogenesis	IGI	J:131426