GO Annotations Graph

• Symbol: Ddx6
• Name: DEAD-box helicase 6
• ID: MGI:104976

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0003729	mRNA binding	IBA	J:265628
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0003724	RNA helicase activity	IEA	J:72247
Molecular Function	GO:0003724	RNA helicase activity	IEA	J:72245
Cellular Component	GO:0005912	adherens junction	ISO	J:155856
Cellular Component	GO:0033391	chromatoid body	ISO	J:155856
Cellular Component	GO:0061830	concave side of sperm head	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:156954
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:164563
Cellular Component	GO:0010494	cytoplasmic stress granule	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0000792	heterochromatin	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005730	nucleolus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0001520	outer dense fiber	ISO	J:155856
Cellular Component	GO:0000932	P-body	IBA	J:265628
Cellular Component	GO:0000932	P-body	ISO	J:168659
Cellular Component	GO:0000932	P-body	IDA	J:217461
Cellular Component	GO:0000932	P-body	ISO	J:73065
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0016442	RISC complex	ISO	J:73065
Cellular Component	GO:0097227	sperm annulus	ISO	J:155856
Biological Process	GO:0035278	miRNA-mediated gene silencing by inhibition of translation	ISO	J:164563
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:217461
Biological Process	GO:0017148	negative regulation of translation	ISO	J:164563
Biological Process	GO:0017148	negative regulation of translation	IBA	J:265628
Biological Process	GO:0030182	neuron differentiation	IMP	J:217461
Biological Process	GO:0033962	P-body assembly	ISO	J:164563
Biological Process	GO:0033962	P-body assembly	IBA	J:265628
Biological Process	GO:0033962	P-body assembly	ISO	J:168659
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:217461
Biological Process	GO:0034063	stress granule assembly	IBA	J:265628
Biological Process	GO:0019074	viral RNA genome packaging	ISO	J:164563