GO Annotations Graph

• Symbol: Ahr
• Name: aryl-hydrocarbon receptor
• ID: MGI:105043

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0017162	aryl hydrocarbon receptor binding	IPI	J:206107
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:200218
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:153
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:242131
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:75462
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:14760
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:153
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TAS	J:65378
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:131871
Molecular Function	GO:0070888	E-box binding	IDA	J:162974
Molecular Function	GO:0051879	Hsp90 protein binding	ISO	J:164563
Molecular Function	GO:0051879	Hsp90 protein binding	TAS	J:175170
Molecular Function	GO:0042802	identical protein binding	IPI	J:206107
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:155856
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:477
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:300865
Molecular Function	GO:0005515	protein binding	IPI	J:162974
Molecular Function	GO:0005515	protein binding	IPI	J:156084
Molecular Function	GO:0005515	protein binding	IPI	J:217463
Molecular Function	GO:0005515	protein binding	IPI	J:31945
Molecular Function	GO:0005515	protein binding	IPI	J:238807
Molecular Function	GO:0005515	protein binding	IPI	J:80189
Molecular Function	GO:0005515	protein binding	IPI	J:261828
Molecular Function	GO:0005515	protein binding	IPI	J:206107
Molecular Function	GO:0005515	protein binding	IPI	J:242131
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0046982	protein heterodimerization activity	IDA	J:242131
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0046982	protein heterodimerization activity	IPI	J:148077
Molecular Function	GO:0046982	protein heterodimerization activity	IDA	J:238807
Molecular Function	GO:0046982	protein heterodimerization activity	IDA	J:206107
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:206107
Molecular Function	GO:0051087	protein-folding chaperone binding	IPI	J:236961
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:861
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	IDA	J:242131
Molecular Function	GO:0017025	TBP-class protein binding	ISO	J:164563
Molecular Function	GO:0001094	TFIID-class transcription factor complex binding	ISO	J:164563
Molecular Function	GO:0015643	toxic substance binding	ISO	J:155856
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IBA	J:265628
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:164563
Cellular Component	GO:0034751	aryl hydrocarbon receptor complex	TAS	J:175170
Cellular Component	GO:0034751	aryl hydrocarbon receptor complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:242131
Cellular Component	GO:0005737	cytoplasm	IDA	J:80189
Cellular Component	GO:0005829	cytosol	IDA	J:175170
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0034752	cytosolic aryl hydrocarbon receptor complex	TAS	J:175170
Cellular Component	GO:0034753	nuclear aryl hydrocarbon receptor complex	ISO	J:164563
Cellular Component	GO:0034753	nuclear aryl hydrocarbon receptor complex	TAS	J:175170
Cellular Component	GO:0005634	nucleus	IDA	J:162974
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:242131
Cellular Component	GO:0005634	nucleus	IDA	J:477
Cellular Component	GO:0005634	nucleus	IDA	J:175170
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:300865
Cellular Component	GO:0005634	nucleus	ISO	J:200218
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	TAS	J:65378
Biological Process	GO:0030183	B cell differentiation	TAS	J:175187
Biological Process	GO:0001782	B cell homeostasis	IMP	J:25048
Biological Process	GO:0001782	B cell homeostasis	TAS	J:175187
Biological Process	GO:0001922	B-1 B cell homeostasis	TAS	J:175187
Biological Process	GO:0008015	blood circulation	IMP	J:64483
Biological Process	GO:0001568	blood vessel development	IMP	J:64483
Biological Process	GO:0097746	blood vessel diameter maintenance	IMP	J:135797
Biological Process	GO:0048514	blood vessel morphogenesis	IMP	J:64483
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:64483
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IMP	J:64483
Biological Process	GO:0043010	camera-type eye development	IMP	J:64483
Biological Process	GO:0019933	cAMP-mediated signaling	ISO	J:164563
Biological Process	GO:0003214	cardiac left ventricle morphogenesis	IMP	J:126182
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0000902	cell morphogenesis	IMP	J:135797
Biological Process	GO:0000902	cell morphogenesis	IMP	J:64483
Biological Process	GO:1904613	cellular response to 2,3,7,8-tetrachlorodibenzodioxine	ISO	J:164563
Biological Process	GO:1904613	cellular response to 2,3,7,8-tetrachlorodibenzodioxine	ISO	J:155856
Biological Process	GO:1904613	cellular response to 2,3,7,8-tetrachlorodibenzodioxine	IDA	J:300865
Biological Process	GO:1904682	cellular response to 3-methylcholanthrene	IDA	J:477
Biological Process	GO:0071320	cellular response to cAMP	ISO	J:164563
Biological Process	GO:1904322	cellular response to forskolin	ISO	J:164563
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	ISO	J:164563
Biological Process	GO:0032922	circadian regulation of gene expression	IDA	J:162974
Biological Process	GO:0003243	circumferential growth involved in left ventricle morphogenesis	IMP	J:126182
Biological Process	GO:0061009	common bile duct development	IMP	J:135797
Biological Process	GO:0006351	DNA-templated transcription	ISO	J:75462
Biological Process	GO:0035162	embryonic hemopoiesis	IMP	J:135797
Biological Process	GO:0048732	gland development	IMP	J:126176
Biological Process	GO:0072102	glomerulus morphogenesis	IMP	J:126182
Biological Process	GO:0002376	immune system process	IMP	J:25048
Biological Process	GO:0060993	kidney morphogenesis	IMP	J:126182
Biological Process	GO:0001889	liver development	IMP	J:135797
Biological Process	GO:0001889	liver development	IMP	J:25048
Biological Process	GO:0001889	liver development	IMP	J:33827
Biological Process	GO:0001889	liver development	IMP	J:64483
Biological Process	GO:0002260	lymphocyte homeostasis	TAS	J:175187
Biological Process	GO:0002260	lymphocyte homeostasis	IMP	J:25048
Biological Process	GO:0010693	negative regulation of alkaline phosphatase activity	ISO	J:155856
Biological Process	GO:1903170	negative regulation of calcium ion transmembrane transport	ISO	J:155856
Biological Process	GO:2000279	negative regulation of DNA biosynthetic process	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:162974
Biological Process	GO:0050728	negative regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0060547	negative regulation of necrotic cell death	IMP	J:135797
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	ISO	J:155856
Biological Process	GO:0033689	negative regulation of osteoblast proliferation	ISO	J:155856
Biological Process	GO:0003085	negative regulation of systemic arterial blood pressure	IMP	J:126182
Biological Process	GO:0002841	negative regulation of T cell mediated immune response to tumor cell	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:131871
Biological Process	GO:0045906	negative regulation of vasoconstriction	IMP	J:126182
Biological Process	GO:0001541	ovarian follicle development	ISO	J:155856
Biological Process	GO:0045793	positive regulation of cell size	IMP	J:64483
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:162974
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:153
Biological Process	GO:0040010	positive regulation of growth rate	IMP	J:33827
Biological Process	GO:0040010	positive regulation of growth rate	IMP	J:25048
Biological Process	GO:0045899	positive regulation of RNA polymerase II transcription preinitiation complex assembly	IDA	J:14760
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0035166	post-embryonic hemopoiesis	IMP	J:33827
Biological Process	GO:0030850	prostate gland development	IMP	J:126176
Biological Process	GO:0030850	prostate gland development	IMP	J:126176
Biological Process	GO:0002819	regulation of adaptive immune response	ISO	J:164563
Biological Process	GO:0030888	regulation of B cell proliferation	ISO	J:164563
Biological Process	GO:0008217	regulation of blood pressure	TAS	J:135797
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:75462
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:477
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	ISO	J:164563
Biological Process	GO:0060420	regulation of heart growth	TAS	J:126182
Biological Process	GO:0060420	regulation of heart growth	TAS	J:135797
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0048608	reproductive structure development	IMP	J:126176
Biological Process	GO:0014070	response to organic cyclic compound	ISO	J:155856
Biological Process	GO:0009636	response to toxic substance	ISO	J:164563
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	IDA	J:22133
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0048745	smooth muscle tissue development	IMP	J:135797
Biological Process	GO:0048536	spleen development	IMP	J:25048
Biological Process	GO:0048536	spleen development	IMP	J:33827
Biological Process	GO:0043029	T cell homeostasis	IMP	J:25048
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:477
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0060841	venous blood vessel development	IMP	J:135797
Biological Process	GO:0006805	xenobiotic metabolic process	TAS	J:5822