GO Annotations Graph

• Symbol: Psmc5
• Name: protease (prosome, macropain) 26S subunit, ATPase 5
• ID: MGI:105047

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:155856
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0140296	general transcription initiation factor binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0036402	proteasome-activating activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:213904
Molecular Function	GO:0005515	protein binding	IPI	J:41266
Molecular Function	GO:0005515	protein binding	IPI	J:148303
Molecular Function	GO:0005102	signaling receptor binding	IPI	J:30618
Molecular Function	GO:0017025	TBP-class protein binding	ISO	J:155856
Molecular Function	GO:0031531	thyrotropin-releasing hormone receptor binding	ISO	J:164563
Molecular Function	GO:0008134	transcription factor binding	ISO	J:164563
Molecular Function	GO:0008134	transcription factor binding	ISA	J:41266
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0031597	cytosolic proteasome complex	ISO	J:155856
Cellular Component	GO:0016234	inclusion body	ISO	J:155856
Cellular Component	GO:0031595	nuclear proteasome complex	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0022624	proteasome accessory complex	IDA	J:188902
Cellular Component	GO:0000502	proteasome complex	ISO	J:155856
Cellular Component	GO:0000502	proteasome complex	ISO	J:164563
Cellular Component	GO:0005838	proteasome regulatory particle	IDA	J:162790
Cellular Component	GO:0008540	proteasome regulatory particle, base subcomplex	IBA	J:265628
Cellular Component	GO:0005675	transcription factor TFIIH holo complex	ISO	J:41266
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:41266
Biological Process	GO:0090261	positive regulation of inclusion body assembly	ISO	J:155856
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0030163	protein catabolic process	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563