GO Annotations Graph

• Symbol: Mtf2
• Name: metal response element binding transcription factor 2
• ID: MGI:105050

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0035064	methylated histone binding	IDA	J:196212
Molecular Function	GO:0035064	methylated histone binding	ISO	J:164563
Molecular Function	GO:0035064	methylated histone binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:157724
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:20197
Molecular Function	GO:0001222	transcription corepressor binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:157068
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0006325	chromatin organization	IBA	J:265628
Biological Process	GO:0040029	epigenetic regulation of gene expression	IMP	J:170279
Biological Process	GO:0040029	epigenetic regulation of gene expression	IMP	J:157068
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0007379	segment specification	IMP	J:170279
Biological Process	GO:0048863	stem cell differentiation	IMP	J:157068
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:157068