GO Annotations Graph

• Symbol: Hsph1
• Name: heat shock 105kDa/110kDa protein 1
• ID: MGI:105053

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000774	adenyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0043014	alpha-tubulin binding	IDA	J:172890
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0140662	ATP-dependent protein folding chaperone	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:86751
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	TAS	J:172886
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-3221864
Cellular Component	GO:0005874	microtubule	IDA	J:172890
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0051085	chaperone cofactor-dependent protein refolding	IDA	J:86751
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	TAS	J:172890
Biological Process	GO:0045345	positive regulation of MHC class I biosynthetic process	TAS	J:172886
Biological Process	GO:0051135	positive regulation of NK T cell activation	TAS	J:172886
Biological Process	GO:0006457	protein folding	IBA	J:265628
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	NAS	J:172890
Biological Process	GO:0006986	response to unfolded protein	TAS	J:52826