Cdh5 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cdh5
cadherin 5
MGI:105057

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0070700	BMP receptor binding	ISO	J:164563
Molecular Function	GO:0045296	cadherin binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0070051	fibrinogen binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:156243
Molecular Function	GO:0005515	protein binding	IPI	J:200401
Molecular Function	GO:0005515	protein binding	IPI	J:98324
Molecular Function	GO:0005515	protein binding	IPI	J:114547
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:164563
Molecular Function	GO:0019903	protein phosphatase binding	IPI	J:114547
Molecular Function	GO:1990782	protein tyrosine kinase binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0043184	vascular endothelial growth factor receptor 2 binding	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IDA	J:235423
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0005912	adherens junction	IDA	J:143865
Cellular Component	GO:0005923	bicellular tight junction	IBA	J:265628
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:94757
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:94757
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:94757
Cellular Component	GO:0016342	catenin complex	IBA	J:265628
Cellular Component	GO:0030054	cell junction	IDA	J:152727
Cellular Component	GO:0071944	cell periphery	IDA	J:132871
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	ISO	J:146528
Cellular Component	GO:0005911	cell-cell junction	IDA	J:98324
Cellular Component	GO:0005911	cell-cell junction	IDA	J:177528
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:199353
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:235423
Biological Process	GO:0034332	adherens junction organization	ISO	J:164563
Biological Process	GO:0034332	adherens junction organization	IBA	J:265628
Biological Process	GO:0070830	bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:0043534	blood vessel endothelial cell migration	ISO	J:164563
Biological Process	GO:0001955	blood vessel maturation	IMP	J:98466
Biological Process	GO:0001955	blood vessel maturation	IMP	J:98466
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0000902	cell morphogenesis	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	ISO	J:164563
Biological Process	GO:0098609	cell-cell adhesion	IC	J:94757
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:177528
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	ISO	J:164563
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	IBA	J:265628
Biological Process	GO:0007043	cell-cell junction assembly	ISO	J:164563
Biological Process	GO:0007043	cell-cell junction assembly	IBA	J:265628
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IEA	J:72247
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:98324
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0031115	negative regulation of microtubule polymerization	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:1903142	positive regulation of establishment of endothelial barrier	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0035307	positive regulation of protein dephosphorylation	ISO	J:164563
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:1902396	protein localization to bicellular tight junction	ISO	J:164563
Biological Process	GO:2000114	regulation of establishment of cell polarity	ISO	J:164563
Biological Process	GO:2000114	regulation of establishment of cell polarity	IMP	J:170050
Biological Process	GO:2000114	regulation of establishment of cell polarity	IBA	J:265628
Biological Process	GO:0001932	regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0043114	regulation of vascular permeability	ISO	J:164563
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0001944	vasculature development	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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