GO Annotations Graph

• Symbol: Rab7
• Name: RAB7, member RAS oncogene family
• ID: MGI:105068

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003925	G protein activity	IEA	J:72245
Molecular Function	GO:0019003	GDP binding	ISO	J:164563
Molecular Function	GO:0019003	GDP binding	ISO	J:155856
Molecular Function	GO:0005525	GTP binding	ISO	J:155856
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:211452
Molecular Function	GO:0005515	protein binding	IPI	J:163139
Molecular Function	GO:0005515	protein binding	IPI	J:206933
Molecular Function	GO:0005515	protein binding	IPI	J:236517
Molecular Function	GO:0005515	protein binding	IPI	J:278051
Molecular Function	GO:0005515	protein binding	IPI	J:197308
Molecular Function	GO:0005515	protein binding	IPI	J:150874
Molecular Function	GO:0005515	protein binding	IPI	J:197308
Molecular Function	GO:1905394	retromer complex binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	ISO	J:155856
Cellular Component	GO:0097208	alveolar lamellar body	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:139000
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:224803
Cellular Component	GO:0005768	endosome	IDA	J:230059
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:67373
Cellular Component	GO:0005770	late endosome	ISO	J:155856
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IBA	J:265628
Cellular Component	GO:0005770	late endosome	IDA	J:240360
Cellular Component	GO:0005770	late endosome	IDA	J:229208
Cellular Component	GO:0005770	late endosome	IDA	J:192731
Cellular Component	GO:0005770	late endosome	IDA	J:95873
Cellular Component	GO:0005770	late endosome	IDA	J:167591
Cellular Component	GO:0005770	late endosome	IDA	J:153178
Cellular Component	GO:0005770	late endosome	IDA	J:323230
Cellular Component	GO:0005770	late endosome	IDA	J:79316
Cellular Component	GO:0005770	late endosome	IDA	J:209071
Cellular Component	GO:0005770	late endosome	ISO	J:89488
Cellular Component	GO:0005770	late endosome	IDA	J:210609
Cellular Component	GO:0005770	late endosome	IDA	J:201826
Cellular Component	GO:0031902	late endosome membrane	IDA	J:224803
Cellular Component	GO:0005811	lipid droplet	IDA	J:224803
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:224803
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IBA	J:265628
Cellular Component	GO:0005764	lysosome	IDA	J:278051
Cellular Component	GO:0005764	lysosome	ISO	J:89488
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0045335	phagocytic vesicle	ISO	J:164563
Cellular Component	GO:0045335	phagocytic vesicle	IBA	J:265628
Cellular Component	GO:0034045	phagophore assembly site membrane	IDA	J:213901
Cellular Component	GO:0030904	retromer complex	ISO	J:164563
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Biological Process	GO:0000045	autophagosome assembly	ISO	J:164563
Biological Process	GO:0006914	autophagy	IEA	J:60000
Biological Process	GO:0045453	bone resorption	ISO	J:155856
Biological Process	GO:0045022	early endosome to late endosome transport	ISO	J:164563
Biological Process	GO:0008333	endosome to lysosome transport	ISO	J:164563
Biological Process	GO:0008333	endosome to lysosome transport	IBA	J:265628
Biological Process	GO:0099638	endosome to plasma membrane protein transport	ISO	J:164563
Biological Process	GO:0007174	epidermal growth factor catabolic process	ISO	J:164563
Biological Process	GO:0051650	establishment of vesicle localization	IMP	J:278051
Biological Process	GO:0006886	intracellular protein transport	TAS	J:67373
Biological Process	GO:0046907	intracellular transport	ISO	J:164563
Biological Process	GO:0016042	lipid catabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0061724	lipophagy	IMP	J:224803
Biological Process	GO:1903542	negative regulation of exosomal secretion	ISO	J:164563
Biological Process	GO:0090383	phagosome acidification	ISO	J:164563
Biological Process	GO:0090385	phagosome-lysosome fusion	ISO	J:164563
Biological Process	GO:0090385	phagosome-lysosome fusion	IBA	J:265628
Biological Process	GO:1903543	positive regulation of exosomal secretion	ISO	J:164563
Biological Process	GO:0045732	positive regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0048524	positive regulation of viral process	ISO	J:164563
Biological Process	GO:0006622	protein targeting to lysosome	ISO	J:164563
Biological Process	GO:0022615	protein to membrane docking	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0009617	response to bacterium	ISO	J:164563
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	ISO	J:164563
Biological Process	GO:0019076	viral release from host cell	ISO	J:164563