GO Annotations Graph

• Symbol: Hsd17b4
• Name: hydroxysteroid (17-beta) dehydrogenase 4
• ID: MGI:105089

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0106386	(3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity	IEA	J:72245
Molecular Function	GO:0044594	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	ISO	J:155856
Molecular Function	GO:0044594	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	IBA	J:265628
Molecular Function	GO:0018812	3-hydroxyacyl-CoA dehydratase activity	ISO	J:155856
Molecular Function	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	IBA	J:265628
Molecular Function	GO:0033989	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity	IEA	J:72245
Molecular Function	GO:0004300	enoyl-CoA hydratase activity	ISO	J:164563
Molecular Function	GO:0004300	enoyl-CoA hydratase activity	IBA	J:265628
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	ISO	J:164563
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0016853	isomerase activity	IEA	J:60000
Molecular Function	GO:0016508	long-chain-enoyl-CoA hydratase activity	ISO	J:164563
Molecular Function	GO:0016508	long-chain-enoyl-CoA hydratase activity	ISO	J:164563
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:296126
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005782	peroxisomal matrix	TAS	Reactome:R-MMU-9034351
Cellular Component	GO:0005777	peroxisome	ISO	J:164563
Cellular Component	GO:0005777	peroxisome	ISO	J:155856
Cellular Component	GO:0005777	peroxisome	IBA	J:265628
Cellular Component	GO:0005777	peroxisome	IDA	J:84795
Biological Process	GO:0008209	androgen metabolic process	ISO	J:164563
Biological Process	GO:0008210	estrogen metabolic process	ISO	J:164563
Biological Process	GO:0006635	fatty acid beta-oxidation	ISO	J:164563
Biological Process	GO:0006635	fatty acid beta-oxidation	IBA	J:265628
Biological Process	GO:0006635	fatty acid beta-oxidation	IMP	J:121804
Biological Process	GO:0006631	fatty acid metabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0036112	medium-chain fatty-acyl-CoA metabolic process	ISO	J:164563
Biological Process	GO:0060009	Sertoli cell development	IMP	J:108368
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	IMP	J:108368
Biological Process	GO:0036111	very long-chain fatty-acyl-CoA metabolic process	ISO	J:164563