GO Annotations Graph

• Symbol: Pgf
• Name: placental growth factor
• ID: MGI:105095

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042056	chemoattractant activity	IBA	J:265628
Molecular Function	GO:0008083	growth factor activity	ISO	J:164563
Molecular Function	GO:0008083	growth factor activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0005172	vascular endothelial growth factor receptor binding	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	ISO	J:58706
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:223264
Cellular Component	GO:0016020	membrane	IEA	J:72247
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IDA	J:85564
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0050930	induction of positive chemotaxis	IBA	J:265628
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:155856
Biological Process	GO:0045766	positive regulation of angiogenesis	IBA	J:265628
Biological Process	GO:0051781	positive regulation of cell division	IEA	J:60000
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	IBA	J:265628
Biological Process	GO:0060754	positive regulation of mast cell chemotaxis	IBA	J:265628
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IBA	J:265628
Biological Process	GO:0060688	regulation of morphogenesis of a branching structure	IDA	J:85564
Biological Process	GO:0001666	response to hypoxia	IBA	J:265628
Biological Process	GO:0002040	sprouting angiogenesis	ISO	J:155856
Biological Process	GO:0002040	sprouting angiogenesis	IBA	J:265628
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IBA	J:265628
Biological Process	GO:0038084	vascular endothelial growth factor signaling pathway	IBA	J:265628