GO Annotations Graph

• Symbol: P2ry2
• Name: purinergic receptor P2Y, G-protein coupled 2
• ID: MGI:105107

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031686	A1 adenosine receptor binding	ISO	J:155856
Molecular Function	GO:0031686	A1 adenosine receptor binding	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0045028	G protein-coupled purinergic nucleotide receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0045030	G protein-coupled UTP receptor activity	ISO	J:155856
Molecular Function	GO:0045030	G protein-coupled UTP receptor activity	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Biological Process	GO:0097746	blood vessel diameter maintenance	ISO	J:155856
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:145117
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0070254	mucus secretion	IMP	J:145117
Biological Process	GO:0070254	mucus secretion	IMP	J:145117
Biological Process	GO:0030279	negative regulation of ossification	ISO	J:155856
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0032722	positive regulation of chemokine production	ISO	J:155856
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0070257	positive regulation of mucus secretion	IMP	J:145117
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0060406	positive regulation of penile erection	ISO	J:155856
Biological Process	GO:0032308	positive regulation of prostaglandin secretion	ISO	J:155856
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	ISO	J:155856
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	ISO	J:155856
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000