GO Annotations Graph

• Symbol: Atp2b2
• Name: ATPase, Ca++ transporting, plasma membrane 2
• ID: MGI:105368

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	IEA	J:72247
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0030899	calcium-dependent ATPase activity	IMP	J:131135
Molecular Function	GO:0005516	calmodulin binding	ISO	J:164563
Molecular Function	GO:0035254	glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0005388	P-type calcium transporter activity	ISO	J:155856
Molecular Function	GO:0005388	P-type calcium transporter activity	ISO	J:164563
Molecular Function	GO:0005388	P-type calcium transporter activity	TAS	Reactome:R-MMU-9668464
Molecular Function	GO:0005388	P-type calcium transporter activity	IBA	J:265628
Molecular Function	GO:1905059	P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	ISO	J:164563
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:164563
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0030165	PDZ domain binding	IBA	J:265628
Molecular Function	GO:0005215	transporter activity	IEA	J:72247
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:131135
Cellular Component	GO:0005929	cilium	IDA	J:56737
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0032591	dendritic spine membrane	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:119503
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:164563
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326638
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326638
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:56737
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IDA	J:56737
Cellular Component	GO:0032809	neuronal cell body membrane	ISO	J:155856
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	ISO	J:155856
Cellular Component	GO:0098684	photoreceptor ribbon synapse	IDA	J:326638
Cellular Component	GO:0098684	photoreceptor ribbon synapse	IDA	J:326638
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9668464
Cellular Component	GO:0005886	plasma membrane	IDA	J:119503
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	IBA	J:265628
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:326638
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:326638
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:326638
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:326638
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	IMP	J:121326
Biological Process	GO:0070588	calcium ion transmembrane transport	IEA	J:72247
Biological Process	GO:0006816	calcium ion transport	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	IMP	J:119503
Biological Process	GO:0006816	calcium ion transport	IMP	J:93962
Biological Process	GO:0006816	calcium ion transport	IMP	J:119503
Biological Process	GO:0000902	cell morphogenesis	IMP	J:56737
Biological Process	GO:0021707	cerebellar granule cell differentiation	IMP	J:48863
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IMP	J:48863
Biological Process	GO:0021692	cerebellar Purkinje cell layer morphogenesis	IMP	J:121220
Biological Process	GO:0021549	cerebellum development	IMP	J:111625
Biological Process	GO:0046068	cGMP metabolic process	IMP	J:18352
Biological Process	GO:0046068	cGMP metabolic process	IMP	J:19948
Biological Process	GO:0090102	cochlea development	IMP	J:48863
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	IMP	J:108937
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:119503
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:119503
Biological Process	GO:0048839	inner ear development	IMP	J:121326
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:48863
Biological Process	GO:0060113	inner ear receptor cell differentiation	IMP	J:121326
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:119503
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:102783
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:119503
Biological Process	GO:0007595	lactation	IMP	J:93962
Biological Process	GO:0040011	locomotion	IMP	J:111625
Biological Process	GO:0007626	locomotory behavior	IMP	J:110607
Biological Process	GO:0007626	locomotory behavior	IMP	J:19948
Biological Process	GO:0007626	locomotory behavior	IMP	J:48863
Biological Process	GO:0007626	locomotory behavior	IMP	J:19947
Biological Process	GO:0007626	locomotory behavior	IMP	J:18352
Biological Process	GO:0007626	locomotory behavior	IMP	MGI:MGI:49803
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:48863
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:110607
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:92390
Biological Process	GO:0070050	neuron cellular homeostasis	IMP	J:102783
Biological Process	GO:0070050	neuron cellular homeostasis	IMP	J:119503
Biological Process	GO:0070050	neuron cellular homeostasis	IMP	J:119503
Biological Process	GO:0030182	neuron differentiation	ISO	J:164563
Biological Process	GO:0006996	organelle organization	IMP	J:121326
Biological Process	GO:0045299	otolith mineralization	IMP	J:48863
Biological Process	GO:0051928	positive regulation of calcium ion transport	IMP	J:131135
Biological Process	GO:0008361	regulation of cell size	IMP	J:121326
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	ISO	J:164563
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	IMP	J:119503
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	IBA	J:265628
Biological Process	GO:0048167	regulation of synaptic plasticity	IMP	J:121220
Biological Process	GO:0007605	sensory perception of sound	ISO	J:164563
Biological Process	GO:0007605	sensory perception of sound	IMP	J:48863
Biological Process	GO:0007605	sensory perception of sound	IMP	J:48969
Biological Process	GO:0007605	sensory perception of sound	IMP	J:71283
Biological Process	GO:0007605	sensory perception of sound	IMP	J:119503
Biological Process	GO:0007605	sensory perception of sound	IGI	J:38429
Biological Process	GO:0007605	sensory perception of sound	IMP	J:108881
Biological Process	GO:0007605	sensory perception of sound	IMP	J:119503
Biological Process	GO:0007605	sensory perception of sound	IMP	J:110607
Biological Process	GO:0007605	sensory perception of sound	IMP	J:92390
Biological Process	GO:0007605	sensory perception of sound	IMP	J:38429
Biological Process	GO:0007605	sensory perception of sound	IMP	J:48969
Biological Process	GO:0042428	serotonin metabolic process	IMP	J:19947
Biological Process	GO:0050808	synapse organization	IMP	J:13355