Ednra GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ednra
endothelin receptor type A
MGI:105923

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004962	endothelin receptor activity	ISO	J:155856
Molecular Function	GO:0004962	endothelin receptor activity	IMP	J:46639
Molecular Function	GO:0004930	G protein-coupled receptor activity	TAS	J:72781
Molecular Function	GO:0005515	protein binding	IPI	J:72781
Molecular Function	GO:0005515	protein binding	IPI	J:72781
Molecular Function	GO:0005515	protein binding	IPI	J:46639
Cellular Component	GO:0071944	cell periphery	IDA	J:290945
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0031965	nuclear membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IGI	J:101241
Biological Process	GO:0001525	angiogenesis	IGI	J:201133
Biological Process	GO:0035904	aorta development	IMP	J:86476
Biological Process	GO:0035904	aorta development	IMP	J:279375
Biological Process	GO:0035904	aorta development	IMP	J:279375
Biological Process	GO:0014824	artery smooth muscle contraction	ISO	J:164563
Biological Process	GO:0003228	atrial cardiac muscle tissue development	IMP	J:166932
Biological Process	GO:0003228	atrial cardiac muscle tissue development	IMP	J:166932
Biological Process	GO:0048675	axon extension	IMP	J:133765
Biological Process	GO:0007411	axon guidance	IMP	J:133765
Biological Process	GO:0060385	axonogenesis involved in innervation	IMP	J:250662
Biological Process	GO:0060385	axonogenesis involved in innervation	IMP	J:274700
Biological Process	GO:0060385	axonogenesis involved in innervation	IMP	J:250662
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:216371
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IMP	J:204461
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IMP	J:204461
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:102130
Biological Process	GO:0070588	calcium ion transmembrane transport	IMP	J:293877
Biological Process	GO:0070588	calcium ion transmembrane transport	IGI	J:293877
Biological Process	GO:0070588	calcium ion transmembrane transport	IDA	J:293877
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:293877
Biological Process	GO:0003207	cardiac chamber formation	IMP	J:166932
Biological Process	GO:0003207	cardiac chamber formation	IMP	J:166932
Biological Process	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	IMP	J:279375
Biological Process	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	IMP	J:279375
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	IDA	J:145765
Biological Process	GO:0044751	cellular response to human chorionic gonadotropin stimulus	IMP	J:145765
Biological Process	GO:0044751	cellular response to human chorionic gonadotropin stimulus	IDA	J:145765
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ISO	J:290945
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ISO	J:290945
Biological Process	GO:0071373	cellular response to luteinizing hormone stimulus	IDA	J:145765
Biological Process	GO:0071260	cellular response to mechanical stimulus	ISO	J:155856
Biological Process	GO:0071310	cellular response to organic substance	ISO	J:290945
Biological Process	GO:0071310	cellular response to organic substance	IMP	J:290945
Biological Process	GO:0071310	cellular response to organic substance	IMP	J:290945
Biological Process	GO:0071310	cellular response to organic substance	IDA	J:290945
Biological Process	GO:0034599	cellular response to oxidative stress	IMP	J:246633
Biological Process	GO:1904888	cranial skeletal system development	IMP	J:149166
Biological Process	GO:1904888	cranial skeletal system development	IMP	J:118663
Biological Process	GO:1904888	cranial skeletal system development	IDA	J:131382
Biological Process	GO:1904888	cranial skeletal system development	IMP	J:131382
Biological Process	GO:1904888	cranial skeletal system development	IMP	J:149166
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:274700
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:166932
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:274700
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:250662
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:274700
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:279375
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:274700
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:250662
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:279375
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:250662
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:274700
Biological Process	GO:0048706	embryonic skeletal system development	IGI	J:224515
Biological Process	GO:0086100	endothelin receptor signaling pathway	IGI	J:293877
Biological Process	GO:0086101	endothelin receptor signaling pathway involved in heart process	IMP	J:279375
Biological Process	GO:0086101	endothelin receptor signaling pathway involved in heart process	IMP	J:279375
Biological Process	GO:0048484	enteric nervous system development	IEA	J:72247
Biological Process	GO:0061028	establishment of endothelial barrier	IDA	J:293570
Biological Process	GO:0060324	face development	IDA	J:131382
Biological Process	GO:0060324	face development	IDA	J:131382
Biological Process	GO:0060324	face development	IMP	J:131382
Biological Process	GO:0060324	face development	IMP	J:131382
Biological Process	GO:0048144	fibroblast proliferation	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	TAS	J:72781
Biological Process	GO:0010467	gene expression	IMP	J:279375
Biological Process	GO:0010467	gene expression	IMP	J:166932
Biological Process	GO:0010467	gene expression	IGI	J:293877
Biological Process	GO:0010467	gene expression	IGI	J:293877
Biological Process	GO:0010467	gene expression	IMP	J:274700
Biological Process	GO:0072011	glomerular endothelium development	IDA	J:297194
Biological Process	GO:0003094	glomerular filtration	ISO	J:155856
Biological Process	GO:0003094	glomerular filtration	IDA	J:297194
Biological Process	GO:0032835	glomerulus development	IMP	J:246633
Biological Process	GO:0060322	head development	IMP	J:93183
Biological Process	GO:0007507	heart development	IMP	J:216371
Biological Process	GO:0007507	heart development	IMP	J:250662
Biological Process	GO:0007507	heart development	IMP	J:250662
Biological Process	GO:0007507	heart development	IGI	J:102130
Biological Process	GO:0007507	heart development	IGI	J:102130
Biological Process	GO:0007507	heart development	IGI	J:102130
Biological Process	GO:0030202	heparin metabolic process	IGI	J:293570
Biological Process	GO:0030202	heparin metabolic process	IGI	J:293570
Biological Process	GO:0001821	histamine secretion	ISO	J:155856
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IGI	J:293877
Biological Process	GO:0001701	in utero embryonic development	IMP	J:93876
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:290945
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ISO	J:290945
Biological Process	GO:0003220	left ventricular cardiac muscle tissue morphogenesis	IMP	J:166932
Biological Process	GO:0003220	left ventricular cardiac muscle tissue morphogenesis	IMP	J:166932
Biological Process	GO:1903537	meiotic cell cycle process involved in oocyte maturation	IMP	J:145765
Biological Process	GO:0097152	mesenchymal cell apoptotic process	IMP	J:118663
Biological Process	GO:0042474	middle ear morphogenesis	IMP	J:149166
Biological Process	GO:0007005	mitochondrion organization	IDA	J:246633
Biological Process	GO:0000278	mitotic cell cycle	IMP	J:166932
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:93876
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:93183
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014032	neural crest cell development	IMP	J:46639
Biological Process	GO:0014033	neural crest cell differentiation	IMP	J:149166
Biological Process	GO:0014033	neural crest cell differentiation	IGI	J:241567
Biological Process	GO:0014033	neural crest cell differentiation	IMP	J:204461
Biological Process	GO:0014033	neural crest cell differentiation	IMP	J:204461
Biological Process	GO:0014033	neural crest cell differentiation	IMP	J:149166
Biological Process	GO:0014034	neural crest cell fate commitment	IMP	J:204461
Biological Process	GO:0014034	neural crest cell fate commitment	IMP	J:204461
Biological Process	GO:0014034	neural crest cell fate commitment	IMP	J:118663
Biological Process	GO:0050905	neuromuscular process	IMP	J:224515
Biological Process	GO:0031175	neuron projection development	IMP	J:250662
Biological Process	GO:0031175	neuron projection development	IMP	J:274700
Biological Process	GO:0016322	neuron remodeling	IMP	J:224515
Biological Process	GO:0003357	noradrenergic neuron differentiation	IMP	J:250662
Biological Process	GO:0003357	noradrenergic neuron differentiation	IMP	J:250662
Biological Process	GO:0042415	norepinephrine metabolic process	IMP	J:216371
Biological Process	GO:0043084	penile erection	ISO	J:155856
Biological Process	GO:0061626	pharyngeal arch artery morphogenesis	IMP	J:279375
Biological Process	GO:0061626	pharyngeal arch artery morphogenesis	IMP	J:204461
Biological Process	GO:0061626	pharyngeal arch artery morphogenesis	IMP	J:279375
Biological Process	GO:0061626	pharyngeal arch artery morphogenesis	IMP	J:204461
Biological Process	GO:0061626	pharyngeal arch artery morphogenesis	IMP	J:204461
Biological Process	GO:1903210	podocyte apoptotic process	IMP	J:246633
Biological Process	GO:0072112	podocyte differentiation	IGI	J:293877
Biological Process	GO:0072112	podocyte differentiation	IDA	J:297194
Biological Process	GO:0072112	podocyte differentiation	IGI	J:293877
Biological Process	GO:0051928	positive regulation of calcium ion transport	ISO	J:155856
Biological Process	GO:2001259	positive regulation of cation channel activity	ISO	J:290945
Biological Process	GO:2001259	positive regulation of cation channel activity	ISO	J:290945
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0050729	positive regulation of inflammatory response	ISO	J:155856
Biological Process	GO:0090184	positive regulation of kidney development	ISO	J:155856
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	ISO	J:155856
Biological Process	GO:0042482	positive regulation of odontogenesis	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	ISO	J:155856
Biological Process	GO:0010737	protein kinase A signaling	ISO	J:290945
Biological Process	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IMP	J:279375
Biological Process	GO:0071806	protein transmembrane transport	IDA	J:293570
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:111842
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:255410
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:213691
Biological Process	GO:0008217	regulation of blood pressure	IGI	J:148635
Biological Process	GO:0008217	regulation of blood pressure	IGI	J:148635
Biological Process	GO:0008217	regulation of blood pressure	IGI	J:111842
Biological Process	GO:0050678	regulation of epithelial cell proliferation	ISO	J:155856
Biological Process	GO:0010827	regulation of glucose transmembrane transport	IDA	J:72781
Biological Process	GO:0002027	regulation of heart rate	IGI	J:111842
Biological Process	GO:0002027	regulation of heart rate	IMP	J:111842
Biological Process	GO:1905871	regulation of protein localization to cell leading edge	IMP	J:279375
Biological Process	GO:0097018	renal albumin absorption	IMP	J:246633
Biological Process	GO:0097018	renal albumin absorption	IDA	J:297194
Biological Process	GO:0097018	renal albumin absorption	IGI	J:293877
Biological Process	GO:0097018	renal albumin absorption	IGI	J:293877
Biological Process	GO:0070294	renal sodium ion absorption	IMP	J:200848
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	IMP	J:46639
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	IMP	J:60070
Biological Process	GO:1905144	response to acetylcholine	IMP	J:255410
Biological Process	GO:0001975	response to amphetamine	IMP	J:250662
Biological Process	GO:0001666	response to hypoxia	IMP	J:46639
Biological Process	GO:0032496	response to lipopolysaccharide	ISO	J:155856
Biological Process	GO:0043278	response to morphine	ISO	J:155856
Biological Process	GO:0010033	response to organic substance	IGI	J:293570
Biological Process	GO:0010033	response to organic substance	IGI	J:293877
Biological Process	GO:0009611	response to wounding	IMP	J:216371
Biological Process	GO:0007266	Rho protein signal transduction	ISO	J:155856
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	IMP	J:274700
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	IMP	J:274700
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	IMP	J:274700
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0048659	smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0055078	sodium ion homeostasis	IGI	J:148635
Biological Process	GO:0042305	specification of segmental identity, mandibular segment	IMP	J:224515
Biological Process	GO:0007382	specification of segmental identity, maxillary segment	IMP	J:224515
Biological Process	GO:0048485	sympathetic nervous system development	IMP	J:216371
Biological Process	GO:0097492	sympathetic neuron axon guidance	IGI	J:274700
Biological Process	GO:0030878	thyroid gland development	IMP	J:228793
Biological Process	GO:0097084	vascular associated smooth muscle cell development	IMP	J:213691
Biological Process	GO:0042310	vasoconstriction	ISO	J:164563
Biological Process	GO:0042310	vasoconstriction	ISO	J:155856
Biological Process	GO:0042310	vasoconstriction	IMP	J:51282

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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