Rab5a GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Rab5a
RAB5A, member RAS oncogene family
MGI:105926

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003925	G protein activity	IEA	J:72245
Molecular Function	GO:0019003	GDP binding	ISO	J:164563
Molecular Function	GO:0051021	GDP-dissociation inhibitor binding	ISO	J:155856
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	TAS	J:18627
Molecular Function	GO:0003924	GTPase activity	IDA	J:81687
Molecular Function	GO:0019001	guanyl nucleotide binding	IDA	J:81687
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:268015
Molecular Function	GO:0005515	protein binding	IPI	J:230616
Molecular Function	GO:0005515	protein binding	IPI	J:161390
Molecular Function	GO:0005515	protein binding	IPI	J:161390
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:175007
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:170947
Cellular Component	GO:0005737	cytoplasm	IDA	J:139000
Cellular Component	GO:0098559	cytoplasmic side of early endosome membrane	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0005769	early endosome	IDA	J:150327
Cellular Component	GO:0005769	early endosome	IDA	J:81687
Cellular Component	GO:0005769	early endosome	IDA	J:106641
Cellular Component	GO:0005769	early endosome	IDA	J:18627
Cellular Component	GO:0005769	early endosome	IDA	J:38944
Cellular Component	GO:0005769	early endosome	IDA	J:90042
Cellular Component	GO:0005769	early endosome	IDA	J:230059
Cellular Component	GO:0005769	early endosome	IDA	J:198162
Cellular Component	GO:0005769	early endosome	ISO	J:89488
Cellular Component	GO:0005769	early endosome	ISO	J:225569
Cellular Component	GO:0005769	early endosome	IDA	J:229208
Cellular Component	GO:0005769	early endosome	ISO	J:73065
Cellular Component	GO:0005769	early endosome	IDA	J:201826
Cellular Component	GO:0005769	early endosome	IDA	J:240360
Cellular Component	GO:0005769	early endosome	IDA	J:126749
Cellular Component	GO:0005769	early endosome	IDA	J:124940
Cellular Component	GO:0005769	early endosome	IDA	J:153178
Cellular Component	GO:0005769	early endosome	IDA	J:202604
Cellular Component	GO:0032009	early phagosome	IDA	J:268015
Cellular Component	GO:0030139	endocytic vesicle	IDA	J:18627
Cellular Component	GO:0012505	endomembrane system	IBA	J:265628
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0005768	endosome	IDA	J:268015
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0005768	endosome	IDA	J:186473
Cellular Component	GO:0005768	endosome	IDA	J:142596
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	IDA	J:79783
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:268015
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:185616
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:18627
Cellular Component	GO:0098842	postsynaptic early endosome	ISO	J:155856
Cellular Component	GO:0098842	postsynaptic early endosome	ISO	J:155856
Cellular Component	GO:0098842	postsynaptic early endosome	IBA	J:265628
Cellular Component	GO:0098844	postsynaptic endocytic zone membrane	ISO	J:155856
Cellular Component	GO:0098844	postsynaptic endocytic zone membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0055037	recycling endosome	ISO	J:155856
Cellular Component	GO:0001726	ruffle	IDA	J:81687
Cellular Component	GO:0001726	ruffle	IDA	J:175007
Cellular Component	GO:0036477	somatodendritic compartment	ISO	J:164563
Cellular Component	GO:0036477	somatodendritic compartment	ISO	J:155856
Cellular Component	GO:0036477	somatodendritic compartment	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	ISO	J:164563
Cellular Component	GO:0042589	zymogen granule membrane	ISO	J:155856
Biological Process	GO:0150093	amyloid-beta clearance by transcytosis	ISO	J:164563
Biological Process	GO:0045022	early endosome to late endosome transport	ISO	J:164563
Biological Process	GO:0006897	endocytosis	ISO	J:164563
Biological Process	GO:0006897	endocytosis	IBA	J:265628
Biological Process	GO:0006897	endocytosis	IDA	J:18627
Biological Process	GO:0006897	endocytosis	IDA	J:81687
Biological Process	GO:0006886	intracellular protein transport	IBA	J:265628
Biological Process	GO:0044788	modulation by host of viral process	ISO	J:164563
Biological Process	GO:0006909	phagocytosis	IEA	J:60000
Biological Process	GO:0045921	positive regulation of exocytosis	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0051036	regulation of endosome size	ISO	J:164563
Biological Process	GO:0051489	regulation of filopodium assembly	ISO	J:164563
Biological Process	GO:0051489	regulation of filopodium assembly	IBA	J:265628
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IBA	J:265628
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	ISO	J:164563
Biological Process	GO:0036465	synaptic vesicle recycling	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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