GO Annotations Graph

• Symbol: Slc16a1
• Name: solute carrier family 16 (monocarboxylic acid transporters), member 1
• ID: MGI:106013

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046943	carboxylic acid transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0015129	lactate transmembrane transporter activity	IMP	J:256529
Molecular Function	GO:0015650	lactate:proton symporter activity	ISO	J:155856
Molecular Function	GO:0015650	lactate:proton symporter activity	ISO	J:164563
Molecular Function	GO:0008028	monocarboxylic acid transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0008028	monocarboxylic acid transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0008028	monocarboxylic acid transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0097159	organic cyclic compound binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:326231
Molecular Function	GO:0015295	solute:proton symporter activity	ISO	J:155856
Molecular Function	GO:0015141	succinate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0009925	basal plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:326231
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:88590
Cellular Component	GO:0005886	plasma membrane	IDA	J:288233
Cellular Component	GO:0005886	plasma membrane	IDA	J:256529
Cellular Component	GO:0045202	synapse	EXP	J:96953
Cellular Component	GO:0045202	synapse	IDA	J:96953
Biological Process	GO:0051780	behavioral response to nutrient	IMP	J:205481
Biological Process	GO:1905039	carboxylic acid transmembrane transport	ISO	J:155856
Biological Process	GO:0071407	cellular response to organic cyclic compound	ISO	J:155856
Biological Process	GO:0007098	centrosome cycle	ISO	J:164563
Biological Process	GO:0042593	glucose homeostasis	IMP	J:192583
Biological Process	GO:0035873	lactate transmembrane transport	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IMP	J:205481
Biological Process	GO:0015718	monocarboxylic acid transport	ISO	J:155856
Biological Process	GO:0015718	monocarboxylic acid transport	ISO	J:164563
Biological Process	GO:0015718	monocarboxylic acid transport	IBA	J:265628
Biological Process	GO:0035879	plasma membrane lactate transport	IMP	J:256529
Biological Process	GO:0035879	plasma membrane lactate transport	ISO	J:155856
Biological Process	GO:0042867	pyruvate catabolic process	IMP	J:256529
Biological Process	GO:1901475	pyruvate transmembrane transport	ISO	J:155856
Biological Process	GO:0050796	regulation of insulin secretion	IMP	J:192583
Biological Process	GO:0032094	response to food	IMP	J:205481
Biological Process	GO:0071422	succinate transmembrane transport	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247