GO Annotations Graph

• Symbol: Ptafr
• Name: platelet-activating factor receptor
• ID: MGI:106066

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045028	G protein-coupled purinergic nucleotide receptor activity	IBA	J:265628
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0001530	lipopolysaccharide binding	IMP	J:38367
Molecular Function	GO:0001875	lipopolysaccharide immune receptor activity	IMP	J:38367
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	ISO	J:155856
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0004992	platelet activating factor receptor activity	ISO	J:164563
Molecular Function	GO:0004992	platelet activating factor receptor activity	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:0006935	chemotaxis	IEA	J:60000
Biological Process	GO:0006935	chemotaxis	IEA	J:72247
Biological Process	GO:0001816	cytokine production	IMP	J:87866
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0006954	inflammatory response	IMP	J:87866
Biological Process	GO:0032959	inositol trisphosphate biosynthetic process	IMP	J:38367
Biological Process	GO:0045776	negative regulation of blood pressure	ISO	J:155856
Biological Process	GO:0007567	parturition	ISO	J:155856
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	ISO	J:164563
Biological Process	GO:0002693	positive regulation of cellular extravasation	ISO	J:155856
Biological Process	GO:1904306	positive regulation of gastro-intestinal system smooth muscle contraction	ISO	J:155856
Biological Process	GO:0060732	positive regulation of inositol phosphate biosynthetic process	ISO	J:155856
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:155856
Biological Process	GO:1903039	positive regulation of leukocyte cell-cell adhesion	ISO	J:155856
Biological Process	GO:1903238	positive regulation of leukocyte tethering or rolling	ISO	J:155856
Biological Process	GO:1904303	positive regulation of maternal process involved in parturition	ISO	J:155856
Biological Process	GO:0043315	positive regulation of neutrophil degranulation	ISO	J:155856
Biological Process	GO:0010863	positive regulation of phospholipase C activity	ISO	J:155856
Biological Process	GO:1904058	positive regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0045987	positive regulation of smooth muscle contraction	ISO	J:155856
Biological Process	GO:1904300	positive regulation of transcytosis	ISO	J:155856
Biological Process	GO:0045727	positive regulation of translation	ISO	J:155856
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:155856
Biological Process	GO:1902943	positive regulation of voltage-gated chloride channel activity	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:38367
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0045056	transcytosis	ISO	J:155856