GO Annotations Graph

• Symbol: Ocln
• Name: occludin
• ID: MGI:106183

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:200231
Molecular Function	GO:0005515	protein binding	IPI	J:75463
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:159723
Cellular Component	GO:0016327	apicolateral plasma membrane	IDA	J:107229
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:236209
Cellular Component	GO:0005923	bicellular tight junction	IBA	J:265628
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:65401
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:124995
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:143865
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:97223
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:117589
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:117344
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:230002
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:200284
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:111967
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:107229
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:87877
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:73065
Cellular Component	GO:0030054	cell junction	ISO	J:73065
Cellular Component	GO:0009986	cell surface	ISO	J:81857
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	IDA	J:280103
Cellular Component	GO:0005911	cell-cell junction	IDA	J:104501
Cellular Component	GO:0005911	cell-cell junction	IDA	J:104501
Cellular Component	GO:0005911	cell-cell junction	IDA	J:104501
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IBA	J:265628
Cellular Component	GO:0030139	endocytic vesicle	IDA	J:200314
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:155856
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:200314
Cellular Component	GO:0005886	plasma membrane	IDA	J:75463
Cellular Component	GO:0005886	plasma membrane	IDA	J:81587
Cellular Component	GO:0005886	plasma membrane	IDA	J:81587
Cellular Component	GO:0005886	plasma membrane	IDA	J:81587
Cellular Component	GO:0005886	plasma membrane	IDA	J:97223
Cellular Component	GO:0005886	plasma membrane	IDA	J:81587
Cellular Component	GO:0005886	plasma membrane	IDA	J:77501
Cellular Component	GO:0005886	plasma membrane	IDA	J:81587
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0070160	tight junction	IDA	J:280385
Cellular Component	GO:0070160	tight junction	IDA	J:200231
Cellular Component	GO:0070160	tight junction	ISO	J:164563
Biological Process	GO:0070830	bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:0070830	bicellular tight junction assembly	IBA	J:265628
Biological Process	GO:0045216	cell-cell junction organization	ISO	J:73065
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:279923
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:1905605	positive regulation of blood-brain barrier permeability	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0046326	positive regulation of glucose import	ISO	J:164563
Biological Process	GO:0010827	regulation of glucose transmembrane transport	ISO	J:164563
Biological Process	GO:0070673	response to interleukin-18	ISO	J:155856
Biological Process	GO:0120193	tight junction organization	IMP	J:280385