Ccr2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ccr2
C-C motif chemokine receptor 2
MGI:106185

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016493	C-C chemokine receptor activity	IDA	J:33019
Molecular Function	GO:0016493	C-C chemokine receptor activity	IDA	J:32263
Molecular Function	GO:0035716	chemokine (C-C motif) ligand 12 binding	IPI	J:37573
Molecular Function	GO:0035715	chemokine (C-C motif) ligand 2 binding	IPI	J:33019
Molecular Function	GO:0071791	chemokine (C-C motif) ligand 5 binding	IBA	J:265628
Molecular Function	GO:0035717	chemokine (C-C motif) ligand 7 binding	IPI	J:33019
Molecular Function	GO:0004950	chemokine receptor activity	IEA	J:72247
Molecular Function	GO:0019955	cytokine binding	IPI	J:32263
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:33019
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:197348
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	J:159685
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISA	J:100459
Cellular Component	GO:0150001	primary dendrite	ISO	J:155856
Biological Process	GO:0001525	angiogenesis	TAS	J:169885
Biological Process	GO:0043277	apoptotic cell clearance	IC	J:33019
Biological Process	GO:0001974	blood vessel remodeling	IEA	J:72247
Biological Process	GO:0006968	cellular defense response	IMP	J:44345
Biological Process	GO:0019725	cellular homeostasis	IDA	J:140759
Biological Process	GO:0070098	chemokine-mediated signaling pathway	ISO	J:155856
Biological Process	GO:0070098	chemokine-mediated signaling pathway	IDA	J:33019
Biological Process	GO:0006935	chemotaxis	IEA	J:72247
Biological Process	GO:0019221	cytokine-mediated signaling pathway	ISO	J:155856
Biological Process	GO:0019221	cytokine-mediated signaling pathway	ISA	J:100459
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IDA	J:33019
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0030097	hemopoiesis	IMP	J:44345
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IMP	J:44561
Biological Process	GO:0006959	humoral immune response	IMP	J:63491
Biological Process	GO:0006955	immune response	IBA	J:265628
Biological Process	GO:0006955	immune response	IMP	J:64054
Biological Process	GO:0006955	immune response	IMP	J:64904
Biological Process	GO:0006955	immune response	IMP	J:62675
Biological Process	GO:0006954	inflammatory response	ISO	J:155856
Biological Process	GO:0006954	inflammatory response	IBA	J:265628
Biological Process	GO:0006954	inflammatory response	IMP	J:64054
Biological Process	GO:0090594	inflammatory response to wounding	IMP	J:261392
Biological Process	GO:0090594	inflammatory response to wounding	IMP	J:269556
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ISO	J:155856
Biological Process	GO:0061756	leukocyte adhesion to vascular endothelial cell	IMP	J:44561
Biological Process	GO:1905517	macrophage migration	IMP	J:269556
Biological Process	GO:0002548	monocyte chemotaxis	IMP	J:208234
Biological Process	GO:0035696	monocyte extravasation	IMP	J:261392
Biological Process	GO:0016525	negative regulation of angiogenesis	IMP	J:147328
Biological Process	GO:0043310	negative regulation of eosinophil degranulation	IMP	J:118487
Biological Process	GO:0002829	negative regulation of type 2 immune response	IMP	J:118487
Biological Process	GO:0097350	neutrophil clearance	IMP	J:44561
Biological Process	GO:0046641	positive regulation of alpha-beta T cell proliferation	IMP	J:118487
Biological Process	GO:2000464	positive regulation of astrocyte chemotaxis	ISO	J:164563
Biological Process	GO:2000451	positive regulation of CD8-positive, alpha-beta T cell extravasation	IMP	J:118487
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:214452
Biological Process	GO:2000473	positive regulation of hematopoietic stem cell migration	IMP	J:159685
Biological Process	GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages	IMP	J:147328
Biological Process	GO:0050729	positive regulation of inflammatory response	IDA	J:159685
Biological Process	GO:0032743	positive regulation of interleukin-2 production	IMP	J:118487
Biological Process	GO:1903238	positive regulation of leukocyte tethering or rolling	IMP	J:44561
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	IMP	J:140759
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	ISO	J:164563
Biological Process	GO:2000439	positive regulation of monocyte extravasation	IMP	J:147328
Biological Process	GO:1904783	positive regulation of NMDA glutamate receptor activity	ISO	J:155856
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	ISO	J:155856
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	IMP	J:269680
Biological Process	GO:0050870	positive regulation of T cell activation	IMP	J:118487
Biological Process	GO:0010820	positive regulation of T cell chemotaxis	IDA	J:140232
Biological Process	GO:0045627	positive regulation of T-helper 1 cell differentiation	IC	J:118487
Biological Process	GO:0002827	positive regulation of T-helper 1 type immune response	IMP	J:125574
Biological Process	GO:2000412	positive regulation of thymocyte migration	IMP	J:269563
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:140759
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:155856
Biological Process	GO:0032729	positive regulation of type II interferon production	IMP	J:118487
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:247722
Biological Process	GO:1905521	regulation of macrophage migration	IMP	J:62675
Biological Process	GO:0071675	regulation of mononuclear cell migration	IMP	J:64904
Biological Process	GO:0071675	regulation of mononuclear cell migration	IMP	J:63491
Biological Process	GO:0002724	regulation of T cell cytokine production	IMP	J:247722
Biological Process	GO:0045580	regulation of T cell differentiation	IMP	J:247722
Biological Process	GO:2000404	regulation of T cell migration	IMP	J:62675
Biological Process	GO:0010574	regulation of vascular endothelial growth factor production	IMP	J:147328
Biological Process	GO:0019233	sensory perception of pain	IMP	J:269680
Biological Process	GO:0019233	sensory perception of pain	IMP	J:84630
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0035705	T-helper 17 cell chemotaxis	IDA	J:140232
Biological Process	GO:0002246	wound healing involved in inflammatory response	NAS	J:159685

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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