GO Annotations Graph

• Symbol: Skil
• Name: SKI-like
• ID: MGI:106203

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:96056
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:177167
Molecular Function	GO:0005515	protein binding	IPI	J:124023
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0046332	SMAD binding	ISO	J:164563
Molecular Function	GO:0046332	SMAD binding	IBA	J:265628
Cellular Component	GO:0001669	acrosomal vesicle	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:136812
Cellular Component	GO:0016605	PML body	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:198828
Biological Process	GO:0001825	blastocyst formation	IMP	J:62174
Biological Process	GO:0030154	cell differentiation	IDA	J:124023
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IMP	J:62174
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IMP	J:62174
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:62174
Biological Process	GO:0070306	lens fiber cell differentiation	IDA	J:124023
Biological Process	GO:0002260	lymphocyte homeostasis	IMP	J:62174
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IBA	J:265628
Biological Process	GO:0045596	negative regulation of cell differentiation	IDA	J:124023
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:136812
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:62174
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:136812
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:96506
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IMP	J:96506
Biological Process	GO:0050772	positive regulation of axonogenesis	ISO	J:164563
Biological Process	GO:0050772	positive regulation of axonogenesis	ISO	J:155856
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	IMP	J:62174
Biological Process	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:62174
Biological Process	GO:0051726	regulation of cell cycle	IMP	J:62174
Biological Process	GO:0051726	regulation of cell cycle	IMP	J:62174
Biological Process	GO:0070848	response to growth factor	ISO	J:164563
Biological Process	GO:0007519	skeletal muscle tissue development	ISO	J:164563
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IGI	J:136812
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IGI	J:136812