GO Annotations Graph

• Symbol: Aqp5
• Name: aquaporin 5
• ID: MGI:106215

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015267	channel activity	IEA	J:72247
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:140476
Molecular Function	GO:0005515	protein binding	IPI	J:140476
Molecular Function	GO:0015250	water channel activity	ISO	J:164563
Molecular Function	GO:0015250	water channel activity	IBA	J:265628
Molecular Function	GO:0015250	water channel activity	TAS	J:65472
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:140476
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:72954
Cellular Component	GO:0009925	basal plasma membrane	IDA	J:105930
Cellular Component	GO:0009925	basal plasma membrane	IDA	J:72954
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:100522
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005902	microvillus	IDA	J:72954
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:76855
Cellular Component	GO:0005886	plasma membrane	TAS	J:65472
Cellular Component	GO:0005886	plasma membrane	IDA	J:105930
Biological Process	GO:0048593	camera-type eye morphogenesis	IMP	J:76855
Biological Process	GO:0015670	carbon dioxide transport	ISO	J:155856
Biological Process	GO:0015670	carbon dioxide transport	ISO	J:164563
Biological Process	GO:0015670	carbon dioxide transport	IBA	J:265628
Biological Process	GO:0071476	cellular hypotonic response	ISO	J:164563
Biological Process	GO:0051289	protein homotetramerization	ISO	J:164563
Biological Process	GO:0046541	saliva secretion	IMP	J:56302
Biological Process	GO:0046541	saliva secretion	IMP	J:62449
Biological Process	GO:0046541	saliva secretion	IMP	J:104681
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0006833	water transport	ISO	J:164563
Biological Process	GO:0006833	water transport	IBA	J:265628
Biological Process	GO:0006833	water transport	TAS	J:65472
Biological Process	GO:0006833	water transport	IMP	J:95030