GO Annotations Graph

• Symbol: Capza1
• Name: capping actin protein of muscle Z-line subunit alpha 1
• ID: MGI:106227

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	IDA	J:125384
Molecular Function	GO:0005515	protein binding	IPI	J:131211
Molecular Function	GO:0005515	protein binding	IPI	J:205441
Cellular Component	GO:0005903	brush border	IDA	J:219622
Cellular Component	GO:0005911	cell-cell junction	IDA	J:205441
Cellular Component	GO:0030863	cortical cytoskeleton	IDA	J:138919
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0008290	F-actin capping protein complex	IBA	J:265628
Cellular Component	GO:0008290	F-actin capping protein complex	IDA	J:131211
Cellular Component	GO:0016020	membrane	IDA	J:138919
Cellular Component	GO:0071203	WASH complex	ISO	J:164563
Biological Process	GO:0030036	actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0051693	actin filament capping	IEA	J:60000
Biological Process	GO:0051016	barbed-end actin filament capping	IBA	J:265628
Biological Process	GO:0051016	barbed-end actin filament capping	IDA	J:125384
Biological Process	GO:0034329	cell junction assembly	ISO	J:164563