GO Annotations Graph

• Symbol: Slx4
• Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
• ID: MGI:106299

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0008047	enzyme activator activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0070522	ERCC4-ERCC1 complex	ISO	J:164563
Cellular Component	GO:0048476	Holliday junction resolvase complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IEA	J:72247
Cellular Component	GO:0033557	Slx1-Slx4 complex	ISO	J:164563
Cellular Component	GO:0033557	Slx1-Slx4 complex	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	ISO	J:164563
Biological Process	GO:0006310	DNA recombination	IEA	J:60000
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0006260	DNA replication	IEA	J:72247
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	ISO	J:164563
Biological Process	GO:0006289	nucleotide-excision repair	ISO	J:164563
Biological Process	GO:1904431	positive regulation of t-circle formation	IMP	J:222674
Biological Process	GO:0032206	positive regulation of telomere maintenance	ISO	J:164563
Biological Process	GO:0000712	resolution of meiotic recombination intermediates	IBA	J:265628
Biological Process	GO:0072429	response to intra-S DNA damage checkpoint signaling	ISO	J:73065
Biological Process	GO:0090656	t-circle formation	ISO	J:164563
Biological Process	GO:0090656	t-circle formation	IMP	J:222674
Biological Process	GO:0061820	telomeric D-loop disassembly	ISO	J:164563