GO Annotations Graph

• Symbol: Rtcb
• Name: RNA 2',3'-cyclic phosphate and 5'-OH ligase
• ID: MGI:106379

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0016874	ligase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0003972	RNA ligase (ATP) activity	ISO	J:164563
Molecular Function	GO:0003972	RNA ligase (ATP) activity	IBA	J:265628
Molecular Function	GO:0008452	RNA ligase activity	IEA	J:72247
Molecular Function	GO:0017166	vinculin binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:162420
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IDA	J:215758
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	IDA	J:215758
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0072669	tRNA-splicing ligase complex	ISO	J:164563
Cellular Component	GO:0072669	tRNA-splicing ligase complex	IBA	J:265628
Biological Process	GO:0001701	in utero embryonic development	IMP	J:162420
Biological Process	GO:0001890	placenta development	IMP	J:162420
Biological Process	GO:0006396	RNA processing	IEA	J:72247
Biological Process	GO:0000971	tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate	IBA	J:265628
Biological Process	GO:0008033	tRNA processing	IEA	J:60000
Biological Process	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	ISO	J:164563