GO Annotations Graph

• Symbol: Tsg101
• Name: tumor susceptibility gene 101
• ID: MGI:106581

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:164563
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:218006
Molecular Function	GO:0005515	protein binding	IPI	J:150398
Molecular Function	GO:0005515	protein binding	IPI	J:81304
Molecular Function	GO:0005515	protein binding	IPI	J:85359
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:81304
Molecular Function	GO:0043130	ubiquitin binding	ISO	J:164563
Molecular Function	GO:0043130	ubiquitin binding	IBA	J:265628
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0046790	virion binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:150398
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0010008	endosome membrane	ISO	J:155856
Cellular Component	GO:0000813	ESCRT I complex	ISO	J:164563
Cellular Component	GO:0000813	ESCRT I complex	NAS	J:231246
Cellular Component	GO:0000813	ESCRT I complex	IBA	J:265628
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0070062	extracellular exosome	IDA	J:209241
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IC	J:81304
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IDA	J:76084
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0008333	endosome to lysosome transport	ISO	J:155856
Biological Process	GO:0008333	endosome to lysosome transport	IBA	J:265628
Biological Process	GO:1990182	exosomal secretion	IMP	J:231246
Biological Process	GO:0006858	extracellular transport	ISO	J:164563
Biological Process	GO:0030216	keratinocyte differentiation	IDA	J:76084
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:76084
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:81304
Biological Process	GO:1903543	positive regulation of exosomal secretion	ISO	J:164563
Biological Process	GO:2000397	positive regulation of ubiquitin-dependent endocytosis	IMP	J:219110
Biological Process	GO:1903774	positive regulation of viral budding via host ESCRT complex	ISO	J:164563
Biological Process	GO:0036211	protein modification process	IEA	J:72247
Biological Process	GO:0006513	protein monoubiquitination	ISO	J:155856
Biological Process	GO:0015031	protein transport	IEA	J:72247
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:76084
Biological Process	GO:0001558	regulation of cell growth	IDA	J:76084
Biological Process	GO:1903551	regulation of extracellular exosome assembly	ISO	J:164563
Biological Process	GO:0040008	regulation of growth	IEA	J:60000
Biological Process	GO:0043405	regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:0046755	viral budding	ISO	J:164563
Biological Process	GO:0046755	viral budding	IMP	J:150398
Biological Process	GO:0019076	viral release from host cell	ISO	J:164563