GO Annotations Graph

• Symbol: Gpld1
• Name: glycosylphosphatidylinositol specific phospholipase D1
• ID: MGI:106604

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	ISO	J:155856
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	IDA	J:189984
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	IDA	J:190011
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	IDA	J:99694
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	ISO	J:164563
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004630	phospholipase D activity	ISO	J:164563
Molecular Function	GO:0004630	phospholipase D activity	IDA	J:43128
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0017080	sodium channel regulator activity	IMP	J:119868
Cellular Component	GO:0005737	cytoplasm	IDA	J:99694
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031012	extracellular matrix	IBA	J:265628
Cellular Component	GO:0031012	extracellular matrix	IDA	J:99694
Cellular Component	GO:0005576	extracellular region	IDA	J:190011
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IDA	J:189984
Cellular Component	GO:0005615	extracellular space	IDA	J:106052
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0034364	high-density lipoprotein particle	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IDA	J:190011
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:155856
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:164563
Biological Process	GO:0071397	cellular response to cholesterol	ISO	J:164563
Biological Process	GO:0071241	cellular response to inorganic substance	ISO	J:155856
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:164563
Biological Process	GO:0071282	cellular response to iron(II) ion	ISO	J:155856
Biological Process	GO:0071467	cellular response to pH	ISO	J:164563
Biological Process	GO:0071401	cellular response to triglyceride	ISO	J:164563
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0002062	chondrocyte differentiation	IEP	J:99694
Biological Process	GO:0002430	complement receptor mediated signaling pathway	ISO	J:164563
Biological Process	GO:0006507	GPI anchor release	IDA	J:99694
Biological Process	GO:0006507	GPI anchor release	IGI	J:189984
Biological Process	GO:0006507	GPI anchor release	ISO	J:164563
Biological Process	GO:0006507	GPI anchor release	IDA	J:119868
Biological Process	GO:0006507	GPI anchor release	IBA	J:265628
Biological Process	GO:0006507	GPI anchor release	IDA	J:43128
Biological Process	GO:0008286	insulin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010897	negative regulation of triglyceride catabolic process	IDA	J:106052
Biological Process	GO:0001503	ossification	IEP	J:99694
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0010595	positive regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0010907	positive regulation of glucose metabolic process	IDA	J:190286
Biological Process	GO:0010983	positive regulation of high-density lipoprotein particle clearance	IMP	J:106052
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	IDA	J:190286
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	ISO	J:164563
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	IDA	J:189984
Biological Process	GO:0051047	positive regulation of secretion	IMP	J:119868
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	IDA	J:106052
Biological Process	GO:1900076	regulation of cellular response to insulin stimulus	ISO	J:164563
Biological Process	GO:0009749	response to glucose	ISO	J:164563
Biological Process	GO:0070633	transepithelial transport	IMP	J:119868