GO Annotations Graph

• Symbol: Slc30a2
• Name: solute carrier family 30 (zinc transporter), member 2
• ID: MGI:106637

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015297	antiporter activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008324	monoatomic cation transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:241041
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0140826	zinc:proton antiporter activity	ISO	J:164563
Molecular Function	GO:0140826	zinc:proton antiporter activity	IC	J:328862
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:164563
Cellular Component	GO:0005743	mitochondrial inner membrane	IDA	J:328862
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0099503	secretory vesicle	ISO	J:164563
Cellular Component	GO:0042589	zymogen granule membrane	IDA	J:328863
Biological Process	GO:0006882	intracellular zinc ion homeostasis	ISO	J:155856
Biological Process	GO:0006812	monoatomic cation transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0061090	positive regulation of sequestering of zinc ion	ISO	J:164563
Biological Process	GO:0061088	regulation of sequestering of zinc ion	IBA	J:265628
Biological Process	GO:0010043	response to zinc ion	IBA	J:265628
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0140882	zinc export across plasma membrane	ISO	J:164563
Biological Process	GO:0140916	zinc ion import into lysosome	ISO	J:164563
Biological Process	GO:0140917	zinc ion import into mitochondrion	IDA	J:328862
Biological Process	GO:0062111	zinc ion import into organelle	ISO	J:164563
Biological Process	GO:0140914	zinc ion import into secretory vesicle	ISO	J:164563
Biological Process	GO:0140915	zinc ion import into zymogen granule	ISO	J:155856
Biological Process	GO:0071577	zinc ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006829	zinc ion transport	ISO	J:155856