GO Annotations Graph

• Symbol: Zic3
• Name: zinc finger protein of the cerebellum 3
• ID: MGI:106676

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:169807
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:169807
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:169910
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:169807
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:136993
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IMP	J:125110
Cellular Component	GO:0005737	cytoplasm	IDA	J:169910
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:114033
Cellular Component	GO:0005634	nucleus	IDA	J:169910
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:108576
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:108576
Biological Process	GO:0003228	atrial cardiac muscle tissue development	IMP	J:125110
Biological Process	GO:0048318	axial mesoderm development	IGI	J:122556
Biological Process	GO:0007049	cell cycle	IGI	J:121744
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0007417	central nervous system development	IBA	J:265628
Biological Process	GO:0035283	central nervous system segmentation	IGI	J:122556
Biological Process	GO:1904888	cranial skeletal system development	IMP	J:117748
Biological Process	GO:0071907	determination of digestive tract left/right asymmetry	ISO	J:164563
Biological Process	GO:0035545	determination of left/right asymmetry in nervous system	IMP	J:75951
Biological Process	GO:0007368	determination of left/right symmetry	ISO	J:164563
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:93195
Biological Process	GO:0007368	determination of left/right symmetry	IGI	J:108576
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:108576
Biological Process	GO:0071910	determination of liver left/right asymmetry	ISO	J:164563
Biological Process	GO:0035469	determination of pancreatic left/right asymmetry	ISO	J:164563
Biological Process	GO:0009880	embryonic pattern specification	IMP	J:106144
Biological Process	GO:0060324	face development	IMP	J:117748
Biological Process	GO:0030900	forebrain development	IGI	J:121744
Biological Process	GO:0007369	gastrulation	IMP	J:106144
Biological Process	GO:0010467	gene expression	IGI	J:122556
Biological Process	GO:0010467	gene expression	IMP	J:125110
Biological Process	GO:0010467	gene expression	IMP	J:124021
Biological Process	GO:0010467	gene expression	IMP	J:192577
Biological Process	GO:0030718	germ-line stem cell population maintenance	IMP	J:295412
Biological Process	GO:0007507	heart development	IMP	J:117748
Biological Process	GO:0007507	heart development	IMP	J:194989
Biological Process	GO:0007507	heart development	IMP	J:192577
Biological Process	GO:0001947	heart looping	ISO	J:164563
Biological Process	GO:0001947	heart looping	IMP	J:108576
Biological Process	GO:0001947	heart looping	IGI	J:108576
Biological Process	GO:0001947	heart looping	IMP	J:93195
Biological Process	GO:0021766	hippocampus development	IGI	J:121744
Biological Process	GO:0070986	left/right axis specification	IMP	J:117748
Biological Process	GO:0060972	left/right pattern formation	IMP	J:194989
Biological Process	GO:0060972	left/right pattern formation	IMP	J:192577
Biological Process	GO:0035108	limb morphogenesis	IGI	J:181884
Biological Process	GO:0030324	lung development	ISO	J:164563
Biological Process	GO:0098727	maintenance of cell number	IGI	J:121744
Biological Process	GO:0007498	mesoderm development	IMP	J:106144
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	IMP	J:295412
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0001840	neural plate development	IGI	J:122556
Biological Process	GO:0030182	neuron differentiation	IMP	J:121744
Biological Process	GO:0021772	olfactory bulb development	IDA	J:244435
Biological Process	GO:0021772	olfactory bulb development	IGI	J:121744
Biological Process	GO:0042473	outer ear morphogenesis	IMP	J:117748
Biological Process	GO:0048339	paraxial mesoderm development	IGI	J:122556
Biological Process	GO:0007389	pattern specification process	IMP	J:75951
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:169807
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:169807
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:108576
Biological Process	GO:0090009	primitive streak formation	IMP	J:106144
Biological Process	GO:0051090	regulation of DNA-binding transcription factor activity	IMP	J:181884
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0001501	skeletal system development	IMP	J:117748
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:181884
Biological Process	GO:0048863	stem cell differentiation	IDA	J:124021
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:124021