GO Annotations Graph

• Symbol: Slc18a2
• Name: solute carrier family 18 (vesicular monoamine), member 2
• ID: MGI:106677

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005275	amine transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:155856
Molecular Function	GO:1901363	heterocyclic compound binding	ISO	J:155856
Molecular Function	GO:0015311	monoamine:proton antiporter activity	ISO	J:155856
Molecular Function	GO:0015311	monoamine:proton antiporter activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:147424
Molecular Function	GO:0005335	serotonin:sodium:chloride symporter activity	IBA	J:265628
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0044297	cell body	ISO	J:155856
Cellular Component	GO:0042995	cell projection	ISO	J:155856
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0031045	dense core granule	ISO	J:155856
Cellular Component	GO:0098691	dopaminergic synapse	ISO	J:155856
Cellular Component	GO:0098691	dopaminergic synapse	IDA	J:45184
Cellular Component	GO:0098691	dopaminergic synapse	IMP	J:45184
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0098992	neuronal dense core vesicle	ISO	J:155856
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	ISO	J:155856
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0030667	secretory granule membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:45184
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	IBA	J:265628
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	IBA	J:265628
Biological Process	GO:0007568	aging	ISO	J:155856
Biological Process	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle	ISO	J:155856
Biological Process	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle	IBA	J:265628
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0042593	glucose homeostasis	ISO	J:155856
Biological Process	GO:0002553	histamine secretion by mast cell	IMP	J:59362
Biological Process	GO:0051615	histamine uptake	ISO	J:164563
Biological Process	GO:0051615	histamine uptake	ISO	J:155856
Biological Process	GO:0030073	insulin secretion	ISO	J:155856
Biological Process	GO:0007626	locomotory behavior	IMP	J:42811
Biological Process	GO:0015844	monoamine transport	ISO	J:155856
Biological Process	GO:0051589	negative regulation of neurotransmitter transport	ISO	J:155856
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	IMP	J:45184
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	IDA	J:45184
Biological Process	GO:0006836	neurotransmitter transport	ISO	J:155856
Biological Process	GO:0009791	post-embryonic development	IMP	J:42811
Biological Process	GO:0001975	response to amphetamine	IMP	J:42811
Biological Process	GO:0009636	response to toxic substance	IMP	J:42811
Biological Process	GO:0002552	serotonin secretion by mast cell	IMP	J:59362
Biological Process	GO:0051610	serotonin uptake	ISO	J:155856
Biological Process	GO:0051610	serotonin uptake	ISO	J:164563
Biological Process	GO:0099123	somato-dendritic dopamine secretion	ISO	J:155856
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0042908	xenobiotic transport	IEA	J:72247