GO Annotations Graph

• Symbol: Slc18a1
• Name: solute carrier family 18 (vesicular monoamine), member 1
• ID: MGI:106684

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0015311	monoamine:proton antiporter activity	ISO	J:164563
Molecular Function	GO:0015311	monoamine:proton antiporter activity	ISO	J:155856
Molecular Function	GO:0015311	monoamine:proton antiporter activity	ISO	J:164563
Molecular Function	GO:0015311	monoamine:proton antiporter activity	IDA	J:332238
Molecular Function	GO:0005335	serotonin:sodium:chloride symporter activity	ISO	J:155856
Molecular Function	GO:0005335	serotonin:sodium:chloride symporter activity	IBA	J:265628
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0030667	secretory granule membrane	ISO	J:164563
Cellular Component	GO:0045202	synapse	IDA	J:194189
Cellular Component	GO:0045202	synapse	IDA	J:194189
Cellular Component	GO:0045202	synapse	IDA	J:194189
Cellular Component	GO:0045202	synapse	IDA	J:194189
Cellular Component	GO:0045202	synapse	IDA	J:194189
Cellular Component	GO:0045202	synapse	IDA	J:194189
Cellular Component	GO:0045202	synapse	IDA	J:194189
Cellular Component	GO:0045202	synapse	IDA	J:194189
Cellular Component	GO:0045202	synapse	IDA	J:194189
Cellular Component	GO:0030672	synaptic vesicle membrane	IBA	J:265628
Cellular Component	GO:0043195	terminal bouton	IBA	J:265628
Biological Process	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle	IBA	J:265628
Biological Process	GO:0090494	dopamine uptake	ISO	J:164563
Biological Process	GO:0051612	negative regulation of serotonin uptake	ISO	J:155856
Biological Process	GO:0006836	neurotransmitter transport	IEA	J:60000
Biological Process	GO:0051620	norepinephrine uptake	ISO	J:164563
Biological Process	GO:0033603	positive regulation of dopamine secretion	ISO	J:155856
Biological Process	GO:0051610	serotonin uptake	ISO	J:164563
Biological Process	GO:0051610	serotonin uptake	ISO	J:164563
Biological Process	GO:0051610	serotonin uptake	IDA	J:332238
Biological Process	GO:0051610	serotonin uptake	ISO	J:155856
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0042908	xenobiotic transport	IEA	J:72247