GO Annotations Graph

• Symbol: Abi2
• Name: abl interactor 2
• ID: MGI:106913

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0070064	proline-rich region binding	ISO	J:164563
Molecular Function	GO:0017124	SH3 domain binding	ISO	J:164563
Molecular Function	GO:0017124	SH3 domain binding	IBA	J:265628
Molecular Function	GO:0035591	signaling adaptor activity	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005884	actin filament	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IDA	J:95254
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:117719
Cellular Component	GO:0030425	dendrite	IDA	J:95254
Cellular Component	GO:0043197	dendritic spine	IDA	J:95254
Cellular Component	GO:0032433	filopodium tip	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:95254
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:95254
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	IBA	J:265628
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	IDA	J:95254
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	IDA	J:95254
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	IMP	J:95254
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	IDA	J:95254
Cellular Component	GO:0031209	SCAR complex	ISO	J:164563
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0008154	actin polymerization or depolymerization	IEA	J:72247
Biological Process	GO:0043010	camera-type eye development	IMP	J:95254
Biological Process	GO:0016477	cell migration	IMP	J:95254
Biological Process	GO:0016358	dendrite development	IMP	J:95254
Biological Process	GO:0007611	learning or memory	IMP	J:95254
Biological Process	GO:0070309	lens fiber cell morphogenesis	IMP	J:95254
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0001764	neuron migration	IMP	J:95254
Biological Process	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	ISO	J:164563
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:164563
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	ISO	J:117719
Biological Process	GO:0099173	postsynapse organization	IMP	J:95254
Biological Process	GO:0099173	postsynapse organization	IDA	J:95254
Biological Process	GO:0099173	postsynapse organization	IDA	J:95254
Biological Process	GO:0099173	postsynapse organization	IDA	J:95254
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IDA	J:95254
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IDA	J:95254
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IMP	J:95254
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IDA	J:95254
Biological Process	GO:0016601	Rac protein signal transduction	ISO	J:164563
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	IMP	J:95254
Biological Process	GO:0045186	zonula adherens assembly	ISO	J:164563