GO Annotations Graph

• Symbol: Vdac2
• Name: voltage-dependent anion channel 2
• ID: MGI:106915

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097001	ceramide binding	ISO	J:164563
Molecular Function	GO:0015485	cholesterol binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0031210	phosphatidylcholine binding	ISO	J:164563
Molecular Function	GO:0015288	porin activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:319693
Molecular Function	GO:0005515	protein binding	IPI	J:182407
Molecular Function	GO:0005515	protein binding	IPI	J:302631
Molecular Function	GO:0005515	protein binding	IPI	J:185561
Molecular Function	GO:0005515	protein binding	IPI	J:309565
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	ISO	J:164563
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	IBA	J:265628
Cellular Component	GO:0001669	acrosomal vesicle	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:164563
Cellular Component	GO:0042645	mitochondrial nucleoid	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IMP	J:185561
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0046930	pore complex	IEA	J:60000
Cellular Component	GO:0097225	sperm midpiece	IDA	J:319693
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Biological Process	GO:0007339	binding of sperm to zona pellucida	ISO	J:164563
Biological Process	GO:0097345	mitochondrial outer membrane permeabilization	ISO	J:164563
Biological Process	GO:0098656	monoatomic anion transmembrane transport	IEA	J:72247
Biological Process	GO:0006820	monoatomic anion transport	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	IMP	J:182407
Biological Process	GO:0032272	negative regulation of protein polymerization	IMP	J:182407
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247